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Safety & Infection ControlAir embolism → clamp + left side

Central Venous Catheter CareNCLEX cheat sheet

A central venous catheter (PICC, tunneled, non-tunneled, or implanted port) delivers fluids, blood, TPN, or vesicant drugs into a large central vein.

19 key facts 3 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Do

  • Sterile dressing changes
  • Scrub the hub before access
  • Flush per protocol (SASH)

Insert

  • Confirm tip by X-ray first use
  • Trendelenburg + Valsalva on removal

Air Embolism

  • Sudden dyspnea, chest pain, ↓BP
  • Clamp line, LEFT side Trendelenburg

Report

  • Redness, drainage → infection
  • Fever, occlusion, no blood return
Red flag to remember

Sudden chest pain, dyspnea, hypotension, tachycardia, and anxiety suggest air embolism; clamp the line, place in left-side Trendelenburg, give oxygen, and call for help.

Before you read

Test yourself first: 3 questions

Question 1 of 3

A client with a fractured hip is on bed rest awaiting surgery. Which intervention BEST reduces the risk of venous thromboembolism?

What is central venous catheter care?

Care centers on preventing central line-associated bloodstream infection (CLABSI) and air embolism. Key principle: maximal sterile technique on insertion, scrub the hub, and clamp before disconnecting.

Central Venous Catheter Care illustrated

Central Venous Catheter Care — medical illustration
Central Venous Catheter Care — medical illustration. Illustration: BruceBlaus via Wikimedia Commons, CC BY 3.0.

Key points to remember

  • The catheter tip sits in the superior vena cava; correct tip placement is confirmed by X-ray before initial use.
  • Use sterile technique for dressing changes; a transparent dressing is changed every 7 days and gauze every 2 days, or when soiled/loose.
  • Scrub the hub/needleless connector with alcohol or chlorhexidine for 15 seconds and allow to dry before each access.
  • Flush with normal saline before and after use; some lines use a heparin lock per protocol (SAS or SASH method).
  • Air embolism is prevented by clamping the lumen and using Valsalva (bear down) during tubing/cap changes.
  • TPN and vesicants are given centrally because they are too hypertonic or caustic for peripheral veins.

Nursing priorities

  1. Perform sterile dressing changes on schedule and assess the site for redness, drainage, and tenderness.
  2. Scrub the hub and flush per protocol to maintain patency and prevent infection.
  3. Clamp the catheter and have the client perform Valsalva when changing caps or tubing.
  4. Position the client in left Trendelenburg if air embolism is suspected.
  5. Verify tip placement by X-ray before first use of a newly inserted line.

Labs & values

Blood cultures (peripheral and from line) if CLABSI suspected
Monitor glucose closely with TPN (target140 to 180 mg/dL)

Patient teaching

  • Keep the dressing clean, dry, and intact; report if it loosens or the site looks red or drains.
  • Report fever, chills, chest pain, or shortness of breath immediately.
  • Do not let the catheter get wet during bathing unless covered.

Red flags: report now

  • Sudden chest pain, dyspnea, hypotension, tachycardia, and anxiety suggest air embolism; clamp the line, place in left-side Trendelenburg, give oxygen, and call for help.
  • Fever, chills, or redness/drainage at the site suggests CLABSI; report and obtain cultures.
  • Never leave a central line open to air; always clamp before disconnecting.

References

Clinical references for this topic

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