👤 By the CinnaRN Clinical Content Team🕐 Updated 2026-08-23🏷️ Safety & Infection Control🔖 Free to read, print, and share
Also known as: central line · CVC · PICC line · central venous access device
Central Venous Catheter Care — medical illustration. Illustration: BruceBlaus via Wikimedia Commons, CC BY 3.0.
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Use this quick-reference guide to spot, treat, and prevent Central Venous Catheter Care on the NCLEX. Keep it handy during review and on exam day!
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📒 The 1-minute cheat sheet
✅ Do
Sterile dressing changes
Scrub the hub before access
Flush per protocol (SASH)
📌 Insert
Confirm tip by X-ray first use
Trendelenburg + Valsalva on removal
📌 Air Embolism
Sudden dyspnea, chest pain, ↓BP
Clamp line, LEFT side Trendelenburg
🚩 Report
Redness, drainage → infection
Fever, occlusion, no blood return
📚 Central Venous Catheter Care — full study notes
The cheat sheet above is your quick recall card. These notes go deeper — what it is, what to do first, what must be reported, and what to teach.
A central venous catheter (PICC, tunneled, non-tunneled, or implanted port) delivers fluids, blood, TPN, or vesicant drugs into a large central vein. Care centers on preventing central line-associated bloodstream infection (CLABSI) and air embolism. Key principle: maximal sterile technique on insertion, scrub the hub, and clamp before disconnecting.
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Key points
Understand these first
The catheter tip sits in the superior vena cava; correct tip placement is confirmed by X-ray before initial use.
Use sterile technique for dressing changes; a transparent dressing is changed every 7 days and gauze every 2 days, or when soiled/loose.
Scrub the hub/needleless connector with alcohol or chlorhexidine for 15 seconds and allow to dry before each access.
Flush with normal saline before and after use; some lines use a heparin lock per protocol (SAS or SASH method).
Air embolism is prevented by clamping the lumen and using Valsalva (bear down) during tubing/cap changes.
TPN and vesicants are given centrally because they are too hypertonic or caustic for peripheral veins.
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Nursing priorities
What to do, in order
Perform sterile dressing changes on schedule and assess the site for redness, drainage, and tenderness.
Scrub the hub and flush per protocol to maintain patency and prevent infection.
Clamp the catheter and have the client perform Valsalva when changing caps or tubing.
Position the client in left Trendelenburg if air embolism is suspected.
Verify tip placement by X-ray before first use of a newly inserted line.
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Red flags — report now
Escalate immediately
Sudden chest pain, dyspnea, hypotension, tachycardia, and anxiety suggest air embolism; clamp the line, place in left-side Trendelenburg, give oxygen, and call for help.
Fever, chills, or redness/drainage at the site suggests CLABSI; report and obtain cultures.
Never leave a central line open to air; always clamp before disconnecting.
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Labs & values
Numbers to know
Blood cultures (peripheral and from line) if CLABSI suspected
Monitor glucose closely with TPN (target 140 to 180 mg/dL)
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Patient teaching
What patients must know
Keep the dressing clean, dry, and intact; report if it loosens or the site looks red or drains.
Report fever, chills, chest pain, or shortness of breath immediately.
Do not let the catheter get wet during bathing unless covered.
❓ Central Venous Catheter Care: NCLEX FAQs
What are the priority nursing interventions for Central Venous Catheter Care?
Perform sterile dressing changes on schedule and assess the site for redness, drainage, and tenderness. Scrub the hub and flush per protocol to maintain patency and prevent infection. Clamp the catheter and have the client perform Valsalva when changing caps or tubing. Position the client in left Trendelenburg if air embolism is suspected.
What are the warning signs of Central Venous Catheter Care a nurse must report?
Sudden chest pain, dyspnea, hypotension, tachycardia, and anxiety suggest air embolism; clamp the line, place in left-side Trendelenburg, give oxygen, and call for help. Fever, chills, or redness/drainage at the site suggests CLABSI; report and obtain cultures. Never leave a central line open to air; always clamp before disconnecting.
What do I need to know about Central Venous Catheter Care for the NCLEX?
The catheter tip sits in the superior vena cava; correct tip placement is confirmed by X-ray before initial use. Use sterile technique for dressing changes; a transparent dressing is changed every 7 days and gauze every 2 days, or when soiled/loose. Scrub the hub/needleless connector with alcohol or chlorhexidine for 15 seconds and allow to dry before each access. Flush with normal saline before and after use; some lines use a heparin lock per protocol (SAS or SASH method).
What patient teaching is important for Central Venous Catheter Care?
Keep the dressing clean, dry, and intact; report if it loosens or the site looks red or drains. Report fever, chills, chest pain, or shortness of breath immediately. Do not let the catheter get wet during bathing unless covered.
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Quick Tip
The catheter tip sits in the superior vena cava; correct tip placement is confirmed by X-ray before initial use.