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Health Promotion & MaintenanceLive vaccines = ≥ 12 mo

Immunization ScheduleNCLEX cheat sheet

The childhood immunization schedule provides active acquired immunity at the ages when children are most vulnerable to vaccine-preventable diseases.

18 key facts 5 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Birth

  • HepB at birth dose 1

2-6 Mo

  • DTaP, IPV, Hib, PCV, RV
  • Series 2, 4, 6 months

12-15 Mo

  • MMR, varicella = live, ≥ 12 mo
  • Hep A, Hib/PCV boosters

Avoid

  • Live = no immunocompromised/preg
  • Hold if mod-severe illness
  • Mild cold = OK to give
Key takeaway

Hepatitis B is given at birth; the full primary series spans 0-18 months.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A nurse is teaching new parents about recommended infant immunizations. The nurse correctly states that the hepatitis B vaccine series should begin at what age?

What is immunization schedule?

Following the CDC/ACIP schedule is a core well-child nursing responsibility. Key principle: live vaccines (MMR, varicella, rotavirus, intranasal flu) are deferred or avoided in immunocompromised and pregnant clients.

Key points to remember

  • Hepatitis B is given at birth; the full primary series spans 0-18 months.
  • MMR and varicella are live vaccines first given at 12-15 months, with a booster at 4-6 years.
  • Rotavirus is an oral live vaccine; the series must START before 15 weeks and finish by 8 months.
  • DTaP is the pediatric series (under 7 years); Tdap is the adolescent/adult booster given at 11-12 years.
  • HPV vaccine is routinely given at 11-12 years as a 2-dose series.
  • A minor acute illness with low-grade fever is NOT a contraindication to vaccination.

Nursing priorities

  1. Screen for true contraindications (anaphylaxis to a prior dose or component, immunosuppression for live vaccines, encephalopathy after pertussis).
  2. Verify and document the vaccine name, lot number, expiration, site, and route in the immunization record.
  3. Give IM vaccines in the vastus lateralis for infants and the deltoid once the child is walking/older.
  4. Provide the current Vaccine Information Statement (VIS) and obtain informed consent before administering.
  5. Observe for 15-30 minutes after administration for an allergic reaction and have epinephrine available.

Patient teaching

  • Expect mild low-grade fever, fussiness, and soreness or redness at the injection site for 1-2 days.
  • Give weight-based acetaminophen or ibuprofen for fever or pain, and apply a cool compress to the site.
  • Keep an updated immunization record; catch-up schedules exist if doses are missed, so don't restart the series.
  • Spacing or skipping vaccines leaves the child unprotected and increases community disease risk.

Red flags: report now

  • Anaphylaxis (wheezing, hives, hypotension, airway swelling) after a dose is an emergency and a contraindication to future doses.
  • Never give live vaccines (MMR, varicella, rotavirus) to a pregnant or significantly immunocompromised child.
  • Report encephalopathy within 7 days of a prior pertussis-containing vaccine as a contraindication.

References

Clinical references for this topic

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