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Serotonin Syndrome — NCLEX Cheat Sheet

Too much serotonin = hyperthermia

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👤 By the CinnaRN Clinical Content Team 🕐 Updated 2026-07-11 🏷️ Pharmacological Therapies 🔖 Free to read, print, and share

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Use this quick-reference guide to spot, treat, and prevent Serotonin Syndrome on the NCLEX. Keep it handy during review and on exam day!

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Why it happens

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What to look for

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Nursing actions

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Notify / act now

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Onset is rapid (often within 6-24 hours of starting or increasing a serotonergic agent or adding a second one).

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