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Pharmacological Therapies: cheat sheets

High-alert medications, drug classes, side effects, antidotes and safe administration for Pharmacological & Parenteral Therapies.

Updated October 13, 2026 112 cheat sheets No signup

All 112 Pharmacological Therapies cheat sheets

ACE Inhibitors-pril → watch dry cough + K+Acetaminophen and N-acetylcysteineNAC = Tylenol OD antidoteAcetaminophen Poisoning in ChildrenAntidote = N-acetylcysteineAcyclovirAntiviral → push fluids, nephroAdenosineRapid IV push for SVTAlbuterolSABA bronchodilator → relax airwaysAlteplase (tPA)Clot-buster → bleeding is #1 riskAminoglycosides-mycin → oto + nephrotoxicAmiodaroneAntidysrhythmic → V-tach/V-fib/AFibAmitriptylineTCA → lethal in overdose (cardiac)AntacidsNeutralize acid → fast, short reliefAntipsychoticsWatch EPS & metabolic effectsAntiretroviral TherapyART → adherence is everythingAspirin (antiplatelet)Irreversible COX → ↓ platelet aggreg.AtropineSymptomatic bradycardia → 0.5mg IVBenzodiazepinesReversal = flumazenilBeta Blockers-olol → hold if HR < 60BisacodylStimulant laxative → fast actingBupropionAtypical → lowers seizure thresholdBuspironeNon-sedating anxiolytic, slow onsetCalcium Channel Blockers-dipine → ↓ BP, watch edemaCalcium GluconateAntidote for Mg toxicity + ↑K+CephalosporinsPCN cross-allergy + disulfiram rxnClopidogrelAntiplatelet — bleeding riskClozapineAgranulocytosis → monitor ANCCoagulation Studies (PT/INR/aPTT)Warfarin → INR; Heparin → aPTTCorticosteroids-sone → never stop abruptlyCromolynMast cell stabilizer → PREVENTIONDesmopressin (DDAVP)Synthetic ADH → water retentionDigoxin ToxicityDig level > 2.0 ng/mL PopularDiltiazemNon-DHP CCB → slows AV nodeDiphenhydramine1st-gen antihistamine → sedatingDisulfiram and Aversion TherapyAlcohol becomes a violent illnessDobutamineBeta-1 inotrope for HFDocusateStool softener → prevents strainingDopamineDose-dependent effects; central lineEpinephrineAnaphylaxis + cardiac arrest 1st-lineFludrocortisoneMineralocorticoid → retains Na+/waterFluoroquinolonesTendon rupture + QT prolong riskFurosemideLoop diuretic → watch K+Gentamicin (peak and trough)Trough <2, peak 5-10 mcg/mLGlipizide (Sulfonylurea)Stimulates insulin → hypoglycemiaGLP-1 AgonistsWeight loss + pancreatitis riskGlucagonRescue for severe hypoglycemiaGuaifenesinExpectorant → thins secretionsH2 Receptor Blockers-tidine → ↓ acid, weaker than PPIHaloperidolTypical antipsychotic → EPS riskHeparin TherapyMonitor aPTT, antidote protamineHydralazineDirect arteriolar vasodilatorHydrocortisone ReplacementAdrenal insufficiency → never stopInhaled CorticosteroidsAsthma controller → not rescueInsulin Types and TimingRegular = only IV insulinIpratropiumAnticholinergic bronchodilator (SAMA)IsoniazidTB drug → give B6, watch liverIV Therapy and Site CareAssess site q1-2h; change q72-96hLactulose↓ ammonia → treats hepatic enceph.LevothyroxineReplaces thyroid hormone (T4)LithiumTherapeutic 0.6–1.2 mEq/LLithium ToxicityToxic > 1.5 mEq/LLoop DiureticsFurosemide → watch K+ < 3.5LoperamideAntidiarrheal → opioid, no CNSMacrolidesGI upset + QT prolongationMagnesium Sulfate TherapyTherapeutic 4-7 mEq/LMAOIs and TyramineThe diet is the whole drugMetforminHold before contrast dyeMethimazoleHyperthyroid; NOT 1st trimesterMethylphenidateCNS stimulant for ADHDMetoclopramideProkinetic → tardive dyskinesia riskMetronidazoleNO alcohol → disulfiram reactionModerate (Conscious) SedationKeeps protective airway reflexesMontelukastLeukotriene blocker → PREVENTION onlyMorphineHold if RR < 12NaloxoneOpioid OD antidote (Narcan)Neuroleptic Malignant SyndromeAntipsychotic emergency: lead-pipe rigidityNitroglycerinHold if SBP < 90NitroprussideWatch cyanide toxicityOctreotideSomatostatin analog → ↓ secretionsOndansetron5-HT3 blocker → watch QT prolongOpioid Analgesics and NaloxoneRR < 12 → hold opioidOpioid-Induced Respiratory DepressionRR < 8-10 = give naloxonePatient-Controlled AnalgesiaONLY patient pushes buttonPenicillinsWatch anaphylaxis + cross-allergyPhenelzineMAOI → tyramine = HTN crisisPhenytoinTherapeutic 10–20 mcg/mLPotassium ChlorideNEVER IV push → fatalPrednisone (corticosteroid)Never stop abruptlyPropylthiouracil (PTU)Hyperthyroid; safer 1st trimesterProton Pump Inhibitors-prazole → ↓ gastric acid stronglyPseudoephedrineSympathomimetic → ↑ BP & HRRh Incompatibility and RhoGAMRh- mom + Rh+ baby = riskRifampinRed-orange body fluids (harmless)RisperidoneAtypical → ↑prolactinSerotonin SyndromeToo much serotonin = hyperthermiaSertralineSSRI → full effect 4-6 weeksSGLT2 InhibitorsGlucose in urine → UTI riskSodium Polystyrene SulfonateKayexalate → lowers K+ via gutSpironolactoneK+-sparing diuretic → watch hyperK+SSRIs and Serotonin SyndromeOnset takes 4–6 weeksStatins (atorvastatin)Take at night; check liver/muscleSucralfateForms protective ulcer barrierSulfonamidesStevens-Johnson + push fluidsTardive DyskinesiaLate involuntary movements, often irreversibleTetracyclinesNO dairy, NO kids <8, NO pregnancyTheophyllineNarrow range: 10-20 mcg/mLTherapeutic Drug LevelsMemorize narrow-window valuesTotal Parenteral NutritionIV nutrition via central lineTricyclic Antidepressants2-4 weeks to work · lethal in overdoseUterine Tetany and OxytocinStop the Pitocin firstValproic AcidHepatotoxic + teratogenVancomycinMRSA → trough 10-20 mcg/mLVenlafaxineSNRI → may ↑ BP, watch DBPWarfarin TherapyMonitor INR, antidote vit K

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