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Pharmacological TherapiesLoop diuretic → watch K+

FurosemideNCLEX cheat sheet

Furosemide is a loop diuretic that blocks sodium and chloride reabsorption in the loop of Henle, producing rapid, potent diuresis.

22 key facts 5 practice questions Reviewed Oct 2026
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Action

  • Loop diuretic, ↓preload
  • Use: HF, edema, HTN

Labs

  • Hypokalemia: K+ < 3.5 → hold
  • Monitor Na, Mg, glucose, BUN

Watch

  • Ototoxic if IV pushed fast
  • Orthostatic ↓BP, dehydration

Teach

  • Eat high-K foods: banana, OJ
  • Take in morning, daily weight
Red flag to remember

Report potassium below 3.5 mEq/L, muscle cramps, or irregular pulse (hypokalemia risk).

Before you read

Test yourself first: 5 questions

Question 1 of 5

The nurse is teaching a client about furosemide. Which statement by the client indicates a need for further teaching?

What is furosemide?

It is used for edema in heart failure, pulmonary edema, renal disease, and hypertension. Memory aid: 'Lasix LASTS 6 hours and makes you LOSe fluid and K+.' Key principle: it wastes potassium, so monitor for hypokalemia.

Key points to remember

  • Loop diuretics are the most potent diuretics and work even in renal impairment.
  • Causes loss of potassium, magnesium, calcium, and sodium, leading to hypokalemia and hypomagnesemia.
  • IV furosemide must be pushed slowly (no faster than 20 mg/min) to prevent ototoxicity and hearing loss.
  • It is a sulfa-based drug, so cross-sensitivity can occur in sulfa-allergic patients.
  • Loop diuretics potentiate digoxin toxicity because hypokalemia increases digoxin binding.

Nursing priorities

  1. Monitor potassium and replace as ordered; report levels below 3.5 mEq/L before giving more.
  2. Weigh the patient daily at the same time and track strict intake and output.
  3. Monitor blood pressure and assess for orthostatic hypotension before ambulation.
  4. Assess lung sounds and edema to evaluate therapeutic response.
  5. Push IV doses slowly and monitor hearing, especially with renal impairment.

Labs & values

Potassium3.5-5.0 mEq/L
Sodium135-145 mEq/L
Magnesium1.3-2.1 mEq/L
BUN10-20 mg/dL
Creatinine0.6-1.2 mg/dL
Digoxin therapeutic0.5-2.0 ng/mL
3.55.0mEq/L Normal

Patient teaching

  • Take in the morning to avoid nighttime urination.
  • Eat potassium-rich foods such as bananas, oranges, and potatoes.
  • Rise slowly to prevent dizziness and report weight gain over 2-3 lb in a day.

Red flags: report now

  • Report potassium below 3.5 mEq/L, muscle cramps, or irregular pulse (hypokalemia risk).
  • Report new tinnitus or hearing changes (ototoxicity).
  • Hold and report systolic BP below parameters or signs of dehydration.

References

Clinical references for this topic

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