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Alteplase (tPA) — NCLEX Cheat Sheet

Clot-buster → bleeding is #1 risk
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👤 By the CinnaRN Clinical Content Team 🕐 Updated 2026-07-11 🏷️ Pharmacological Therapies 🔖 Free to read, print, and share
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Use this quick-reference guide to spot, treat, and prevent Alteplase (tPA) on the NCLEX. Keep it handy during review and on exam day!

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Uses

Key facts
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Window

Nursing actions
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Avoid

Key facts
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Report

Notify / act now
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Do

Nursing actions
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Quick Tip

Dissolves existing thrombi and must be given within tight time windows (generally within 3-4.5 hours of ischemic stroke symptom onset).

📖 Related Topics

Digoxin ToxicityHeparin TherapyWarfarin TherapyAcetaminophen Poisoning in Children
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