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Pharmacological TherapiesMast cell stabilizer → PREVENTION

CromolynNCLEX cheat sheet

Cromolyn is a mast cell stabilizer that prevents the release of histamine and other inflammatory mediators, used prophylactically for asthma and allergic rhinitis.

14 key facts 1 practice questions Reviewed Oct 2026
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Uses

  • Asthma & allergy prophylaxis
  • Stabilizes mast cells → no histamine

Do

  • Use 15 min before exercise/trigger
  • Scheduled daily → full effect ~2-4 wk

Avoid

  • NOT for acute attack → no rescue

Teach

  • Throat irritation, cough common
  • Gargle/sip water after dose
Red flag to remember

Never rely on cromolyn to relieve an active asthma attack or acute bronchospasm.

Before you read

Test yourself first: 1 question

Question 1 of 1

A nurse is teaching a client prescribed cromolyn sodium by inhalation. Which statement by the nurse is accurate about this medication?

What is cromolyn?

It is a preventive controller drug and has NO effect on an acute attack. Effects build over time, so it must be used consistently.

Key points to remember

  • It is a prophylactic mast cell stabilizer that prevents, but does not relieve, bronchospasm.
  • Full benefit may take 2-4 weeks of regular use.
  • It can be taken before exercise or known allergen exposure to prevent symptoms.
  • It has a very favorable safety profile with minimal systemic side effects.
  • Common minor effects include throat irritation, cough, and bad taste.

Nursing priorities

  1. Reinforce regular scheduled use rather than as-needed use.
  2. Teach pre-dosing before exercise or anticipated allergen exposure.
  3. Continue a separate rescue bronchodilator for acute symptoms.
  4. Teach mouth rinsing or sipping water to ease throat irritation.

Patient teaching

  • Use it on a regular schedule; it may take a few weeks to work fully.
  • Take it before exercise or allergen exposure to prevent symptoms.
  • Keep your rescue inhaler for sudden attacks because this drug will not stop one.

Red flags: report now

  • Never rely on cromolyn to relieve an active asthma attack or acute bronchospasm.
  • Report worsening wheezing or difficulty breathing after a dose (possible bronchospasm).

References

Clinical references for this topic

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