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Safety & Infection ControlSterile field = absolutely no microbes

Surgical AsepsisNCLEX cheat sheet

Surgical asepsis is the practice of rendering and keeping an area and items completely free of all microorganisms and spores, used for invasive procedures and surgery.

15 key facts 3 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

When

  • Surgery, catheter, central line, wounds
  • Any break in skin/sterile cavity

Rules

  • Sterile touches sterile ONLY
  • If doubt = contaminated, discard
  • Keep field in constant view

Do

  • Surgical hand scrub, sterile gloves
  • Add items w/o crossing field

Avoid

  • Never turn back / reach across
  • Moisture wicks microbes → unsterile
Key takeaway

Surgical asepsis eliminates all microorganisms including spores, whereas medical asepsis only reduces their number.

Before you read

Test yourself first: 3 questions

Question 1 of 3

Which describes correct surgical hand antisepsis/asepsis principle?

What is surgical asepsis?

It contrasts with medical asepsis (clean technique), which only reduces the number of organisms. The principle is total absence of microbes within the sterile zone.

Key points to remember

  • Surgical asepsis eliminates all microorganisms including spores, whereas medical asepsis only reduces their number.
  • It is required for surgery, catheter insertion, central line placement, and invasive sterile dressing changes.
  • A surgical scrub uses friction from fingertips to elbows, keeping hands above the elbows so water runs downward.
  • After scrubbing, hands are held up and away from the body to prevent contamination.
  • Sterile items contacting non-sterile surfaces, or any wet sterile field, are considered contaminated.
  • The sterile gown is considered sterile only from chest to waist in front and from the hands to just above the elbows.

Nursing priorities

  1. Perform a surgical scrub with friction, keeping hands higher than elbows throughout.
  2. Dry hands and don sterile gown and gloves without touching non-sterile surfaces.
  3. Maintain awareness of sterile boundaries on the gown and field at all times.
  4. Discard and replace any item or field whose sterility is in question.

Patient teaching

  • Explain to patients that the masked, gowned setup exists to prevent surgical-site infection.
  • Ask patients not to touch sterile drapes or instruments during the procedure.

Red flags: report now

  • When sterility is uncertain, treat the item or field as contaminated and replace it.
  • Never lower scrubbed hands below the elbows or below waist level.
  • Report any contamination event during a sterile procedure immediately.

References

Clinical references for this topic

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