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Metabolic SyndromeNCLEX cheat sheet

Metabolic syndrome is a cluster of cardiometabolic risk factors that together greatly increase the risk of type 2 diabetes, heart disease, and stroke.

22 key facts 3 practice questions Reviewed Oct 2026
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Criteria

  • Waist: M >40", F >35"
  • TG ≥150, HDL low
  • BP ≥130/85, FBG ≥100

Risk

  • ↑risk T2DM, CAD, stroke
  • Insulin resistance = core driver

Do

  • Weight loss, exercise 150 min/wk
  • DASH/Mediterranean diet
  • Statins, metformin as needed
Key takeaway

Diagnosed when 3 or more of these are present: large waist circumference, elevated triglycerides, low HDL, elevated blood pressure, and elevated fasting glucose.

Before you read

Test yourself first: 3 questions

Question 1 of 3

A nurse is counseling parents about newborn sleep safety to reduce the risk of sudden infant death syndrome (SIDS). Which statement indicates correct understanding?

What is metabolic syndrome?

Diagnosis requires at least 3 of 5 criteria centered on central obesity and insulin resistance. Lifestyle modification is the cornerstone of treatment.

Key points to remember

  • Diagnosed when 3 or more of these are present: large waist circumference, elevated triglycerides, low HDL, elevated blood pressure, and elevated fasting glucose.
  • Central (abdominal/visceral) obesity and insulin resistance are the driving features.
  • It substantially raises the risk of type 2 diabetes, atherosclerotic cardiovascular disease, and stroke.
  • Weight loss, increased physical activity, and a heart-healthy diet can reverse or prevent progression.
  • Management targets each component: statins for lipids, antihypertensives for BP, and metformin or lifestyle for glucose.
  • Prevalence rises with age, sedentary lifestyle, and family history of diabetes or cardiovascular disease.

Nursing priorities

  1. Measure waist circumference, blood pressure, and obtain fasting lipid panel and glucose to identify components.
  2. Promote weight loss of 5-10% and at least 150 minutes per week of moderate aerobic activity.
  3. Provide dietary teaching emphasizing reduced refined carbohydrates, saturated fat, and sodium.
  4. Administer and educate on prescribed statins, antihypertensives, and antidiabetic medications.
  5. Encourage smoking cessation and screen for and address obstructive sleep apnea.

Labs & values

Triglycerides ≥150 mg/dL
HDL <40 mg/dL men, <50 mg/dL women
Fasting glucose ≥100 mg/dL
Blood pressure ≥130/85 mmHg
Waist circumference >40 in (102 cm) men, >35 in (88 cm) women

Patient teaching

  • Even modest weight loss of 5-7% significantly lowers diabetes and cardiac risk.
  • Choose whole grains, vegetables, lean protein, and unsaturated fats; limit sugary drinks and processed foods.
  • Regular physical activity improves insulin sensitivity independent of weight loss.
  • Keep follow-up appointments to monitor blood pressure, lipids, and glucose over time.

Red flags: report now

  • New chest pain, dyspnea, or neurologic deficits suggesting an acute cardiovascular or cerebrovascular event.
  • Fasting glucose consistently in the diabetic range (≥126 mg/dL) indicating progression to type 2 diabetes requiring treatment.

References

Clinical references for this topic

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