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OsteoporosisNCLEX cheat sheet

Osteoporosis is a metabolic disease in which bone resorption outpaces bone formation, leaving bones porous, brittle, and prone to fracture.

22 key facts 5 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Labs

  • DEXA T-score ≤ -2.5 = dx
  • Ca, vit D usually normal

Causes

  • Postmenopausal ↓ estrogen
  • Steroids, smoking, ETOH, immobility
  • Thin, white/Asian, low Ca diet

Meds

  • Bisphosphonates: take AM, full glass H2O
  • Sit upright 30 min after dose

Teach

  • Ca + vit D, weight-bearing exercise
  • Fall-proof home, no throw rugs
Key takeaway

It is often asymptomatic until a fragility fracture occurs from minimal trauma.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A 58-year-old postmenopausal woman asks how to reduce her risk of osteoporosis. Which lifestyle recommendation should the nurse include?

What is osteoporosis?

It is called the silent disease because bone loss occurs without symptoms until a fracture happens. Risk is highest in postmenopausal women due to estrogen loss, and common fracture sites are the hip, wrist, and vertebrae.

Osteoporosis illustrated

Osteoporosis: normal versus porous, thinned bone
Osteoporosis: normal versus porous, thinned bone. Illustration: BruceBlaus via Wikimedia Commons, CC BY 3.0.

Key points to remember

  • It is often asymptomatic until a fragility fracture occurs from minimal trauma.
  • Loss of height and a stooped posture (kyphosis or dowager's hump) result from vertebral compression fractures.
  • Major risk factors include postmenopausal estrogen loss, age, low calcium and vitamin D, smoking, alcohol, and steroid use.
  • A DEXA scan T-score of -2.5 or lower confirms osteoporosis; -1.0 to -2.5 is osteopenia.
  • Weight-bearing exercise stimulates bone formation, while immobility accelerates bone loss.
  • Long-term corticosteroid therapy is a leading secondary cause of bone loss.

Common causes

  • Postmenopausal ↓ estrogen
  • Steroids, smoking, ETOH, immobility
  • Thin, white/Asian, low Ca diet

Nursing priorities

  1. Implement fall precautions: clear clutter, ensure good lighting, use non-skid footwear, and provide assistive devices.
  2. Encourage adequate dietary calcium and vitamin D and administer supplements as ordered.
  3. Promote weight-bearing and resistance exercise such as walking.
  4. Administer bisphosphonates correctly and teach proper administration.
  5. Use safe handling and transfer techniques to prevent fractures.

Labs & values

Serum calcium:9.0 to 10.5 mg/dL (often normal in primary osteoporosis)
Vitamin D (25-OH): 30 to 100 ng/mL (often low)
DEXA T-score: -2.5 or lower confirms osteoporosis

Patient teaching

  • Take bisphosphonates (alendronate) on an empty stomach with a full glass of water and remain upright for 30 to 60 minutes to prevent esophageal irritation.
  • Increase intake of calcium-rich foods (dairy, leafy greens) and vitamin D, and stop smoking and limit alcohol.
  • Perform regular weight-bearing exercise and remove home hazards to prevent falls.

Red flags: report now

  • Sudden onset of severe back pain may indicate a vertebral compression fracture and needs evaluation.
  • A fall in an osteoporotic patient should always be assessed for fracture even without obvious deformity.

References

Clinical references for this topic

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