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Physiological AdaptationGlucose < 70 mg/dL

HypoglycemiaNCLEX cheat sheet

Hypoglycemia is a blood glucose below 70 mg/dL.

25 key facts 5 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Signs

  • Shaky, sweaty, tachycardic
  • Confusion, irritable, slurred
  • Seizure, coma if severe

Do

  • Rule of 15: 15g carb, recheck 15min
  • 4 oz juice, glucose tabs
  • Repeat ×3 then protein snack

Unconscious

  • IV D50 if IV access
  • Glucagon IM/SubQ if no IV
  • NPO if can't swallow

Causes

  • Too much insulin, skipped meal
  • Excess exercise, alcohol
Key takeaway

Adrenergic: shakiness, diaphoresis, tachycardia, hunger, anxiety

Before you read

Test yourself first: 5 questions

Question 1 of 5

A home care nurse is teaching a client newly diagnosed with type 2 diabetes about recognizing hypoglycemia. Which symptom should the nurse include?

What is hypoglycemia?

The brain depends on glucose, so symptoms come on fast and are an emergency. A level below 54 mg/dL is clinically significant, and any low glucose with confusion or inability to self-treat is severe hypoglycemia. Causes include too much insulin, skipped meals and extra exercise.

Key points to remember

  • Adrenergic: shakiness, diaphoresis, tachycardia, hunger, anxiety
  • Neuroglycopenic: confusion, slurred speech, blurred vision, seizures, coma
  • Onset is rapid (vs the gradual onset of hyperglycemia)
  • Common triggers: an insulin or sulfonylurea dose that is too high, a late or missed meal, vomiting, extra exercise, alcohol, and worsening kidney function.
  • Beta blockers can hide the tremor and fast heart rate; sweating usually still occurs.
  • Low glucose during the night may show as nightmares, night sweats or a morning headache.

Common causes

  • Too much insulin, skipped meal
  • Excess exercise, alcohol

Signs & symptoms

  • Shaky, sweaty, tachycardic
  • Confusion, irritable, slurred
  • Seizure, coma if severe

Nursing priorities

  1. If conscious: give 15 g fast-acting carbohydrate (4 oz juice, glucose tabs), recheck in 15 min
  2. Repeat the 15/15 rule until glucose > 70, then give a complex carb + protein snack
  3. If unconscious or NPO: IV dextrose 50% (D50) or IM/SubQ glucagon
  4. Check glucose before meals and before giving insulin; hold the dose and notify the provider if it is low.
  5. Once the patient is alert and can swallow, give a snack with carbohydrate and protein, then find and correct the cause.

Labs & values

Blood glucose <70 mg/dL
Fasting glucose70–99 mg/dL (normal)
Below54 mg/dL = clinically significant hypoglycemia

Patient teaching

  • Always carry a fast sugar source; treat early symptoms immediately
  • Recognize that beta blockers can mask the early shaky/tachycardic warning signs
  • Teach family members to give glucagon (injection or nasal) if the person cannot swallow.
  • Check glucose before driving and treat a low reading, then recheck, before getting behind the wheel.

Red flags: report now

  • Unconscious, seizing, or unable to swallow — do NOT give oral food/fluids; use IV D50 or glucagon
  • A glucose below 54 mg/dL, or any confusion, seizure or loss of consciousness, needs immediate treatment.

References

Clinical references for this topic

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