👤 By the CinnaRN Clinical Content Team🕐 Updated 2026-08-23🏷️ Physiological Adaptation🔖 Free to read, print, and share
Also known as: high potassium · high K · potassium excess
Hyperkalemia — medical illustration. Illustration: Jer5150 / Wikimedia Commons via Wikimedia Commons, CC BY-SA 3.0.
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Use this quick-reference guide to spot, treat, and prevent Hyperkalemia on the NCLEX. Keep it handy during review and on exam day!
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📒 The 1-minute cheat sheet
⚠️ Causes
Renal failure = #1 cause
K-sparing diuretics, ACE, ARBs
Acidosis, cell lysis, burns
🩺 Signs
Peaked T waves, wide QRS
Muscle twitch → flaccid paralysis
↑ bowel sounds, diarrhea
🧪 Meds
Ca gluconate → protects heart
Insulin + D50, albuterol shift in
Kayexalate, dialysis remove K+
🚩 Report
Cardiac arrest / lethal arrhythmia
Avoid K+ foods, salt substitutes
📚 Hyperkalemia — full study notes
The cheat sheet above is your quick recall card. These notes go deeper — what it is, what to do first, what must be reported, and what to teach.
Hyperkalemia is a serum potassium above 5.0 mEq/L. Because potassium controls cardiac membrane excitability, a high level is dangerous mainly because of life-threatening dysrhythmias. Common causes are renal failure, potassium-sparing diuretics, ACE inhibitors, Addison's disease, tissue breakdown (crush injury, burns), and acidosis shifting K⁺ out of cells.
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Key points
Understand these first
Earliest signs are muscle twitching/cramps progressing to weakness and flaccid paralysis
ECG changes: tall, peaked T waves, widened QRS, and prolonged PR — can progress to asystole
Renal clients: avoid salt substitutes (they are potassium chloride) and high-K⁺ foods
❓ Hyperkalemia: NCLEX FAQs
What are the priority nursing interventions for Hyperkalemia?
Cardiac monitor — peaked T waves signal emergent risk. Calcium gluconate IV to stabilize the myocardium (does not lower K⁺). Shift K⁺ into cells: IV insulin with dextrose, and/or nebulized albuterol, sodium bicarb if acidotic. Remove K⁺ from the body: sodium polystyrene sulfonate (Kayexalate) or dialysis.
What are the warning signs of Hyperkalemia a nurse must report?
K⁺ > 6.5 mEq/L or peaked T waves / widening QRS — treat as an emergency. Hold ACE inhibitors and potassium-sparing diuretics (spironolactone).
What do I need to know about Hyperkalemia for the NCLEX?
Earliest signs are muscle twitching/cramps progressing to weakness and flaccid paralysis. ECG changes: tall, peaked T waves, widened QRS, and prolonged PR — can progress to asystole. GI: hyperactive bowel sounds, diarrhea, abdominal cramping. Renal failure is the most common cause.
What patient teaching is important for Hyperkalemia?
Renal clients: avoid salt substitutes (they are potassium chloride) and high-K⁺ foods.
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Quick Tip
Earliest signs are muscle twitching/cramps progressing to weakness and flaccid paralysis.