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Hyponatremia — NCLEX Cheat Sheet

Na+ < 135 mEq/L
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👤 By the CinnaRN Clinical Content Team 🕐 Updated 2026-08-23 🏷️ Physiological Adaptation 🔖 Free to read, print, and share

Also known as: low sodium · low Na

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Use this quick-reference guide to spot, treat, and prevent Hyponatremia on the NCLEX. Keep it handy during review and on exam day!

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📒 The 1-minute cheat sheet

⚠️ Causes

  • SIADH, water excess, CHF
  • Diuretics, vomiting, diarrhea
  • Excess hypotonic IV / D5W

🩺 Signs

  • Confusion, HA, lethargy
  • Seizures, coma if severe
  • N/V, muscle cramps, ↓ DTRs

✅ Do

  • Restrict fluids if dilutional
  • Hypertonic 3% NaCl → slow, ICU
  • Seizure precautions, safety

📌 Avoid

  • Fast correction → demyelination
  • Daily wts, strict I&O

📚 Hyponatremia — full study notes

The cheat sheet above is your quick recall card. These notes go deeper — what it is, what to do first, what must be reported, and what to teach.

Hyponatremia is a serum sodium below 135 mEq/L. Sodium drives osmolality and water balance, so a low level pulls water into cells — the brain is most vulnerable, making neurologic changes the central concern. Causes include SIADH, excess water intake, diuretics, and GI losses.
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Key points

Understand these first

Nursing priorities

What to do, in order
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Red flags — report now

Escalate immediately
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Labs & values

Numbers to know

❓ Hyponatremia: NCLEX FAQs

What are the priority nursing interventions for Hyponatremia?

Restrict fluids when the cause is dilutional/SIADH. Give hypertonic saline (3%) ONLY for severe, symptomatic hyponatremia, slowly. Institute seizure precautions and monitor neuro status closely. Correct sodium slowly — rapid correction risks osmotic demyelination.

What are the warning signs of Hyponatremia a nurse must report?

New seizures, worsening confusion, or Na⁺ < 120 mEq/L — notify provider now. Do NOT correct sodium too fast (> 8–12 mEq/L in 24 h).

What do I need to know about Hyponatremia for the NCLEX?

Neurologic: headache, confusion, lethargy progressing to seizures and coma. GI: nausea, vomiting, abdominal cramping. Muscle weakness and cramps; possible hypotension if volume-depleted.

What lab values are associated with Hyponatremia?

Serum sodium 135–145 mEq/L (hyponatremia < 135).

Quick Tip

Neurologic: headache, confusion, lethargy progressing to seizures and coma.

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