CinnaRN Start free
Physiological AdaptationPost-strep, tea-colored urine

Acute GlomerulonephritisNCLEX cheat sheet

Acute glomerulonephritis is inflammation of the glomeruli, often an immune response 1-3 weeks after a streptococcal infection of the throat or skin (post-streptococcal glomerulonephritis).

24 key facts 3 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Mech

  • post-strep, 1-2 wks after infection
  • immune complexes inflame glomeruli

Signs

  • tea/cola-colored urine (hematuria)
  • HTN, periorbital/facial edema
  • proteinuria (mild), oliguria

Labs

  • ↑ASO titer, ↑BUN ↑creat
  • ↓complement (C3)

Do

  • restrict Na, fluid, protein
  • antibiotics, antihypertensives
  • monitor BP, I&O, daily weight
  • report ↓urine, ↑edema, ↑BP
Red flag to remember

Severe hypertension, headache, or visual changes - risk of hypertensive encephalopathy; report immediately.

Before you read

Test yourself first: 3 questions

Question 1 of 3

A client having an acute asthma attack has wheezing and uses accessory muscles. The priority intervention is to:

What is acute glomerulonephritis?

Antigen-antibody complexes deposit in the glomeruli, impairing filtration. It is most common in children and usually self-limiting, but matters because it causes fluid retention and hypertension.

Acute Glomerulonephritis illustrated

Glomerulus: normal vs nephrotic syndrome (protein leak) vs glomerulonephritis (red cells leak)
Glomerulus: normal vs nephrotic syndrome (protein leak) vs glomerulonephritis (red cells leak). Illustration: CinnaRN.

Key points to remember

  • Classic signs are hematuria producing tea-colored or cola-colored urine, proteinuria, and oliguria.
  • Periorbital and facial edema with hypertension occur from fluid retention.
  • A recent strep throat or skin infection precedes symptoms by about 1-3 weeks.
  • Antistreptolysin O (ASO) titer is elevated, confirming a recent streptococcal infection.
  • BUN and creatinine may rise temporarily as filtration is impaired.
  • Unlike nephrotic syndrome, protein loss is mild-to-moderate and hematuria is the dominant feature.

Signs & symptoms

  • tea/cola-colored urine (hematuria)
  • HTN, periorbital/facial edema
  • proteinuria (mild), oliguria

Nursing priorities

  1. Monitor blood pressure, daily weights, intake/output, and urine color.
  2. Restrict sodium and fluids; restrict protein and potassium if azotemia is present.
  3. Administer antibiotics to eradicate residual streptococcal infection and antihypertensives/diuretics as ordered.
  4. Promote rest during the acute phase to reduce metabolic demand.
  5. Monitor for signs of fluid overload and worsening renal function.

Labs & values

ASO titer: elevated (confirms recent strep)
Urinalysis: hematuria, proteinuria, RBC casts
BUN: normal10-20 mg/dL (may rise); Creatinine 0.6-1.2 mg/dL (may rise)

Patient teaching

  • Complete the full antibiotic course and treat strep infections promptly to prevent recurrence.
  • Follow sodium and fluid restrictions and rest during recovery.
  • Report decreased urine output, swelling, headache, or dark urine.

Red flags: report now

  • Severe hypertension, headache, or visual changes - risk of hypertensive encephalopathy; report immediately.
  • Signs of fluid overload/pulmonary edema (dyspnea, crackles) - escalate.
  • Worsening oliguria or rising creatinine signaling progression to renal failure - report.
  • Seizures or decreased level of consciousness - emergency.

References

Clinical references for this topic

CinnaRN website
CinnaRN app: a cheat sheet in the study feed
Study Acute Glomerulonephritis in the app4,000+ NCLEX questions with a rationale on every answer, NGN case studies and timed mock exams.See how CinnaRN works
Start free
Want more Physiological Adaptation questions?We'll email you a free set on Acute Glomerulonephritis. No account needed.

Was this helpful?

Free to start

Know acute glomerulonephritis cold

4,000+ NCLEX questions with a rationale on every answer, NGN case studies and timed mock exams.

  • 4,000+ NCLEX questions with rationales
  • 51 NGN case studies
  • Timed CAT-style mock exams
  • 500+ cheat sheets
See how CinnaRN works
CinnaRN website
CinnaRN app: a cheat sheet in the study feed