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Physiological AdaptationIrregular, no P waves

Atrial FibrillationNCLEX cheat sheet

Atrial fibrillation is a rapid, disorganized atrial rhythm in which the atria quiver instead of contracting effectively, producing an irregularly irregular heartbeat.

22 key facts 5 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Signs

  • Irregularly irregular pulse
  • Palpitations, fatigue, SOB
  • Apical-radial pulse deficit

Report

  • Stroke risk from clots
  • Rapid RVR → ↓ CO

Meds

  • Anticoagulate (warfarin/DOAC)
  • Rate control: BB, CCB, dig
  • Cardioversion (TEE first)

Teach

  • Bleeding precautions on AC
  • Consistent vit K if warfarin
Key takeaway

The hallmark is an irregularly irregular pulse with no identifiable P waves on the ECG.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A nurse is preparing to assist with synchronized cardioversion. Which statement correctly distinguishes synchronized cardioversion from defibrillation?

What is atrial fibrillation?

Because blood pools and stagnates in the fibrillating atria, clots form and can travel to the brain, making stroke the major danger. The loss of the atrial kick reduces cardiac output and may cause fatigue, palpitations, and heart failure.

Atrial Fibrillation illustrated

Atrial fibrillation: disorganized electrical activity in the atria
Atrial fibrillation: disorganized electrical activity in the atria. Illustration: BruceBlaus via Wikimedia Commons, CC BY-SA 4.0.

Key points to remember

  • The hallmark is an irregularly irregular pulse with no identifiable P waves on the ECG.
  • Blood stasis in the left atrium promotes thrombus formation, greatly increasing the risk of embolic stroke.
  • A rapid ventricular response can decrease cardiac output, causing hypotension, dizziness, and dyspnea.
  • Common causes include hypertension, heart failure, valvular disease, hyperthyroidism, and ischemic heart disease.
  • Management focuses on rate control, rhythm control, and anticoagulation to prevent stroke.

Signs & symptoms

  • Irregularly irregular pulse
  • Palpitations, fatigue, SOB
  • Apical-radial pulse deficit

Nursing priorities

  1. Assess apical heart rate, blood pressure, and signs of decreased perfusion, and place on continuous cardiac monitoring.
  2. Administer rate-control agents such as beta-blockers, calcium channel blockers, or digoxin as ordered.
  3. Administer anticoagulation as prescribed to prevent thromboembolic stroke.
  4. Prepare the patient for cardioversion if hemodynamically unstable, ensuring anticoagulation status is verified first.
  5. Monitor for signs of stroke and bleeding throughout treatment.

Labs & values

INR: therapeutic2.0-3.0 for patients on warfarin
Potassium and magnesium levels (electrolyte imbalances can trigger dysrhythmias)
TSH to rule out hyperthyroidism as a cause
2.03.0for Normal

Patient teaching

  • Take anticoagulants exactly as prescribed and never skip doses, as they prevent life-threatening strokes.
  • Check the pulse daily and report a rate that is very fast, very slow, or newly irregular.
  • Avoid excess caffeine and alcohol, watch for bleeding signs, and keep all follow-up and lab appointments.

Red flags: report now

  • New onset of stroke symptoms such as facial droop, slurred speech, or one-sided weakness requires immediate action.
  • Hemodynamic instability with hypotension, chest pain, or syncope demands urgent intervention or cardioversion.
  • Signs of bleeding from anticoagulation such as black stools, hematuria, or severe headache must be reported immediately.

References

Clinical references for this topic

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