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Physiological AdaptationIliac crest, pressure after

Bone Marrow BiopsyNCLEX cheat sheet

A bone marrow biopsy and aspiration remove marrow tissue, usually from the posterior iliac crest, to evaluate blood-cell production and diagnose leukemia, anemias, and other hematologic disorders.

23 key facts 3 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Def

  • Aspirate marrow → posterior iliac crest
  • Dx leukemia, anemia, cancers

Do

  • Prone/side-lying position
  • Pressure 5-10 min after → ↓ bleed
  • Pressure dressing, ice, monitor site

Watch

  • Bleeding risk → check coag/platelets
  • Brief sharp pain on aspiration (normal)

Report

  • Continued bleeding, swelling, fever
  • Site infection, severe pain
Red flag to remember

Report uncontrolled bleeding, an expanding hematoma, or saturated dressing at the site.

Before you read

Test yourself first: 3 questions

Question 1 of 3

A pressure injury reveals full-thickness skin loss with visible subcutaneous fat, but bone, tendon, and muscle are NOT exposed. Slough may be present. How should the nurse stage this wound?

What is bone marrow biopsy?

A local anesthetic is used, but the patient feels brief pressure and a pulling sensation during aspiration. Memory aid: pressure to the site is the key post-procedure action to prevent bleeding.

Key points to remember

  • The posterior iliac crest is the most common site; the sternum may be used for aspiration only in adults.
  • Patients with low platelets or clotting disorders are at higher risk for bleeding after the procedure.
  • The patient feels brief sharp pain or a pulling sensation when marrow is aspirated despite local anesthesia.
  • Firm pressure followed by a pressure dressing to the site controls bleeding afterward.
  • Bleeding and infection at the site are the primary post-procedure complications.
  • The specimen evaluates cellularity, cell lines, and abnormal cells for diagnosis.

Nursing priorities

  1. Verify informed consent and review platelet count and coagulation studies before the procedure.
  2. Position the patient prone or side-lying to expose the iliac crest.
  3. Apply firm direct pressure to the site, then a pressure dressing after the needle is removed.
  4. Monitor the site for bleeding, swelling, or hematoma and assess pain afterward.
  5. Administer prescribed analgesics and monitor for signs of infection.

Labs & values

Platelets:150,000-400,000/mm3
Hemoglobin:12-18 g/dL (varies by sex)
WBC:5,000-10,000/mm3
INR: 0.8-1.1

Patient teaching

  • You will feel pressure and a brief sharp or pulling feeling when the marrow is drawn.
  • Keep the dressing dry and intact, and watch the site for bleeding once home.
  • Mild soreness for a day or two is normal; take pain medicine as directed.
  • Report fever, increasing pain, or bleeding that soaks the dressing.

Red flags: report now

  • Report uncontrolled bleeding, an expanding hematoma, or saturated dressing at the site.
  • Report fever, increasing pain, redness, or drainage suggesting infection.
  • Report signs of shock such as hypotension and tachycardia.
  • Never remove pressure too early in a patient with thrombocytopenia.

References

Clinical references for this topic

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