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Physiological AdaptationWBC, Hgb, Hct, platelets

Complete Blood CountNCLEX cheat sheet

A CBC reports red cells, white cells, hemoglobin, hematocrit, and platelets, screening for anemia, infection, and bleeding risk.

21 key facts 5 practice questions Reviewed Oct 2026
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Wbc

  • Normal 5,000-10,000
  • ↑ infection; ↓ immunocompromised
  • <1,000 neutropenia precautions

Hgb/Hct

  • Hgb M 14-18, F 12-16
  • Hct ≈ 3x Hgb
  • ↓ = anemia/bleed, ↑ = dehydration

Plt

  • Normal 150,000-400,000
  • <50k bleed risk, fall precautions
  • <20k spontaneous bleed

Report

  • WBC <1,000 or Hgb <7
  • PLT <20k → notify MD
Red flag to remember

Platelets under 20,000 carry a risk of spontaneous bleeding and must be reported immediately.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A nurse is reviewing the complete blood count of a client 2 days after a vaginal birth. Which finding is an expected physiologic change of the early postpartum period?

What is complete blood count?

Hemoglobin and hematocrit reflect oxygen-carrying capacity, the WBC count reflects infection or inflammation, and platelets reflect clotting ability. It is one of the most frequently ordered and most heavily tested panels on the NCLEX.

Key points to remember

  • Hematocrit is roughly three times the hemoglobin value when hydration is normal.
  • An elevated WBC suggests infection or inflammation, while a low WBC raises infection risk from immunosuppression.
  • A left shift, meaning more immature neutrophils (bands), indicates an acute active infection.
  • Platelets below 150,000 increase bleeding risk; below 50,000 raises serious bleeding concern.
  • Low hemoglobin and hematocrit indicate anemia or active bleeding and reduce oxygen delivery.
  • Neutropenia, an absolute neutrophil count under 1,000, leaves the patient highly vulnerable to infection.

Nursing priorities

  1. Assess for signs of bleeding, bruising, and petechiae when platelets are low.
  2. Initiate neutropenic precautions and protect the patient from infection when the WBC or ANC is low.
  3. Monitor for fatigue, pallor, tachycardia, and dyspnea when hemoglobin is low.
  4. Hold or question invasive or anticoagulant interventions when platelet counts are critically low.
  5. Trend serial values rather than reacting to a single result to detect active bleeding.

Labs & values

WBC5,000-10,000/mm3
RBC4.2-6.1 million/mm3
Hemoglobin12-18 g/dL (varies by sex)
Hematocrit37-52% (varies by sex)
Platelets150,000-400,000/mm3

Patient teaching

  • Avoid crowds and sick contacts and report any fever when white counts are low.
  • Use a soft toothbrush and an electric razor and avoid contact sports when platelets are low.

Red flags: report now

  • Platelets under 20,000 carry a risk of spontaneous bleeding and must be reported immediately.
  • A new fever in a neutropenic patient is an emergency requiring prompt provider notification and cultures.
  • A rapidly dropping hemoglobin signals active hemorrhage and needs urgent escalation.

References

Clinical references for this topic

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