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Physiological AdaptationScreen 24-28 wks OGTT

Gestational DiabetesNCLEX cheat sheet

Gestational diabetes mellitus (GDM) is glucose intolerance first recognized during pregnancy, caused by placental hormones (such as human placental lactogen) that increase insulin resistance.

20 key facts 5 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Screen

  • 50g GCT at 24-28 wks
  • Fail → 3-hr OGTT confirms

Risk

  • Macrosomia → shoulder dystocia
  • Neonatal hypoglycemia after birth

Meds

  • Diet + exercise first-line
  • Insulin if needed (oral often used too)

Teach

  • Monitor glucose, controlled-carb diet
  • Resolves postpartum, recheck 6-12 wks
Red flag to remember

Report fasting glucose consistently above 95 mg/dL or postprandial values above target, indicating poor control.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A nurse reviews the diagnostic workup for gestational diabetes. Using the 3-hour 100-g oral glucose tolerance test, how many abnormal values are required to confirm the diagnosis?

What is gestational diabetes?

It typically appears in the second or third trimester and usually resolves after delivery. It matters because uncontrolled maternal hyperglycemia leads to a macrosomic infant, birth trauma, and neonatal hypoglycemia after birth.

Key points to remember

  • Placental hormones create insulin resistance, so maternal blood glucose rises, especially after meals.
  • Excess maternal glucose crosses the placenta and stimulates fetal insulin, producing macrosomia (large infant).
  • After birth the high fetal insulin level persists briefly, causing neonatal hypoglycemia.
  • Maternal complications include preeclampsia, polyhydramnios, and an increased rate of cesarean birth.
  • Screening is done with a 1-hour 50 g glucose challenge, confirmed by a 3-hour 100 g oral glucose tolerance test, usually at 24-28 weeks.
  • Women with GDM have a higher lifetime risk of developing type 2 diabetes.

Nursing priorities

  1. Teach and reinforce a controlled-carbohydrate diet and regular physical activity as first-line management.
  2. Instruct on home blood glucose self-monitoring (fasting and postprandial values) and recording results.
  3. Administer insulin as prescribed when diet and exercise do not control glucose (insulin is the preferred drug in pregnancy).
  4. Monitor fetal growth and well-being with ultrasound and nonstress tests as ordered.
  5. After delivery, monitor the newborn closely for hypoglycemia and feed early.

Labs & values

Fasting blood glucose target in pregnancy: under95 mg/dL
1-hour postprandial target: under 140 mg/dL; 2-hour target: under 120 mg/dL1-hour postprandial target: under 140 mg/dL; 2-hour target: under 120 mg/dL
Hemoglobin A1c: ideally under 6% in pregnancy

Patient teaching

  • Check and log blood glucose at the times your provider specifies, and bring records to each visit.
  • Follow the prescribed meal plan with consistent carbohydrate amounts and avoid concentrated sugars.
  • Get tested for type 2 diabetes after the postpartum period because GDM raises your future risk.

Red flags: report now

  • Report fasting glucose consistently above 95 mg/dL or postprandial values above target, indicating poor control.
  • Report signs of macrosomia or polyhydramnios, which raise the risk of shoulder dystocia and birth injury.
  • Assess the newborn for jitteriness, poor feeding, or lethargy, which signal neonatal hypoglycemia requiring immediate feeding or glucose.

References

Clinical references for this topic

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