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Physiological AdaptationTemp > 104°F + no sweat

Heat StrokeNCLEX cheat sheet

Heat stroke is a life-threatening failure of thermoregulation with core temperature above 104 degrees F (40 degrees C) and central nervous system dysfunction.

26 key facts 5 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Signs

  • Hot dry skin, no sweat
  • Altered LOC, confusion, seizure
  • Tachycardia, hypotension

Do

  • Rapid cool = priority
  • Cold packs, mist, fans
  • Cool IV fluids, O2

Monitor

  • Stop cooling at 102°F
  • Watch rhabdo, ↓UO, organ fail

Avoid

  • Antipyretics don't work
  • Shivering from over-cooling
Key takeaway

Core temperature above 104 degrees F (40 degrees C) with neurologic changes (confusion, seizures, coma) defines heat stroke.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A newborn loses heat to the cold metal surface of an unpadded scale during weighing. Which mechanism of heat loss does this represent?

What is heat stroke?

Unlike heat exhaustion, the skin is typically hot and dry because sweating has failed, and altered mental status is a defining feature. Rapid cooling is the priority to prevent organ damage and death.

Key points to remember

  • Core temperature above 104 degrees F (40 degrees C) with neurologic changes (confusion, seizures, coma) defines heat stroke.
  • Classic heat stroke shows hot, dry skin from sweating failure, distinguishing it from heat exhaustion's diaphoresis.
  • Heat exhaustion presents with heavy sweating, normal or mildly elevated temperature, and intact mental status, and is less severe.
  • Rapid active cooling is the priority and should not wait for transport or labs.
  • Complications include rhabdomyolysis, seizures, multi-organ failure, and DIC.
  • Antipyretics like acetaminophen are ineffective because the cause is environmental, not a reset hypothalamic set point.

Signs & symptoms

  • Hot dry skin, no sweat
  • Altered LOC, confusion, seizure
  • Tachycardia, hypotension

Nursing priorities

  1. Begin rapid cooling immediately with evaporative cooling, ice packs to groin/axillae/neck, and cool IV fluids.
  2. Remove clothing and move the patient to a cool environment.
  3. Support airway, give oxygen, and monitor neurologic status and core temperature continuously.
  4. Stop active cooling around 102 degrees F (39 degrees C) to avoid overshoot hypothermia.
  5. Monitor for seizures, dysrhythmias, and signs of rhabdomyolysis.

Labs & values

Core temperature above104 degrees F (40 degrees C)
Creatine kinase markedly elevated with rhabdomyolysis
Potassium elevated with muscle breakdown
Sodium abnormal; monitor renal function (creatinine/BUN)

Patient teaching

  • Avoid strenuous activity during peak heat and take frequent breaks in the shade.
  • Hydrate with water and electrolyte drinks before and during heat exposure.
  • Never leave children or pets in parked cars.
  • Wear light, loose, breathable clothing in hot weather.

Red flags: report now

  • Hot dry skin with altered mental status is heat stroke - cool aggressively and escalate now.
  • Do not give antipyretics; they do not work for environmental hyperthermia.
  • Report dark tea-colored urine as possible rhabdomyolysis and renal injury.
  • Seizures or coma indicate severe CNS injury requiring emergency intervention.

References

Clinical references for this topic

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