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Huntington Disease — NCLEX Cheat Sheet

Autosomal dominant → chorea + dementia
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👤 By the CinnaRN Clinical Content Team 🕐 Updated 2026-08-23 🏷️ Physiological Adaptation 🔖 Free to read, print, and share

Also known as: Huntington chorea · HD · hereditary chorea

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Use this quick-reference guide to spot, treat, and prevent Huntington Disease on the NCLEX. Keep it handy during review and on exam day!

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📒 The 1-minute cheat sheet

📌 Mech

  • Autosomal dominant, CAG repeat
  • Basal ganglia degeneration
  • Onset age 30-50

🩺 Signs

  • Chorea: jerky involuntary moves
  • Progressive dementia
  • Mood swings, depression

✅ Do

  • Aspiration precautions
  • High-calorie soft diet
  • Safety: pad, prevent injury

🚩 Report

  • No cure → supportive care
  • Suicide risk, genetic counseling

📚 Huntington Disease — full study notes

The cheat sheet above is your quick recall card. These notes go deeper — what it is, what to do first, what must be reported, and what to teach.

Huntington disease is an inherited, autosomal-dominant, progressive degenerative disorder of the basal ganglia and cerebral cortex causing involuntary movements (chorea), progressive dementia, and emotional disturbance. Symptoms usually begin between ages 30 and 50, after most patients have already had children, and the disease is relentlessly progressive over 10 to 20 years. Each child of an affected parent has a 50 percent chance of inheriting the gene. There is no cure; treatment is symptomatic and supportive.
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Key points

Understand these first

Nursing priorities

What to do, in order
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Red flags — report now

Escalate immediately
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Patient teaching

What patients must know

❓ Huntington Disease: NCLEX FAQs

What are the priority nursing interventions for Huntington Disease?

Prevent aspiration: assess swallowing, provide thickened liquids and soft foods, position upright for meals, and have suction available. Maximize caloric intake with high-calorie, high-protein foods because constant movement greatly increases metabolic demand. Maintain safety: pad the environment, use proper positioning and seating, and implement fall and injury precautions. Assess mood and screen for suicidal ideation; provide emotional support and psychiatric referral.

What are the warning signs of Huntington Disease a nurse must report?

Expressed suicidal ideation or a plan — initiate suicide precautions and notify the provider immediately. Coughing, choking, or new fever with meals indicating aspiration — stop oral intake and reassess swallowing.

What do I need to know about Huntington Disease for the NCLEX?

Autosomal-dominant inheritance: each offspring of an affected parent has a 50 percent chance of inheriting the defective gene, and genetic testing can confirm the diagnosis. Classic triad: choreiform (jerky, writhing, uncontrollable) movements, progressive cognitive decline/dementia, and psychiatric/behavioral changes including depression and irritability. Chorea and dysphagia worsen over time, leading to high risk for falls, aspiration, malnutrition, and weight loss. No cure exists; tetrabenazine and deutetrabenazine reduce chorea, and antipsychotics/antidepressants manage behavioral symptoms.

What patient teaching is important for Huntington Disease?

Offer genetic counseling to the patient and at-risk family members; testing can be done before symptoms appear. Eat frequent high-calorie, high-protein meals and use soft or thickened foods to reduce choking and meet energy needs. Use safety measures such as padded surfaces, supportive seating, and fall precautions as movements worsen. Recognize and report signs of depression or thoughts of self-harm.

Quick Tip

Autosomal-dominant inheritance: each offspring of an affected parent has a 50 percent chance of inheriting the defective gene, and genetic testing can confirm the diagnosis.

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