👤 By the CinnaRN Clinical Content Team🕐 Updated 2026-08-23🏷️ Physiological Adaptation🔖 Free to read, print, and share
Also known as: alkalosis · high pH · high bicarb · alkaline blood
Metabolic Alkalosis — medical illustration. Illustration: OpenStax via Wikimedia Commons, CC BY 3.0.
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Use this quick-reference guide to spot, treat, and prevent Metabolic Alkalosis on the NCLEX. Keep it handy during review and on exam day!
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📒 The 1-minute cheat sheet
🧪 Labs
pH > 7.45, HCO₃ > 26
Lungs retain CO₂ (slow/shallow)
🩺 Signs
↓ K → cramps, weakness
Tetany, tingling, tremor
Dizzy, confusion, ↑ DTRs
🚩 Report
Dysrhythmias from ↓ K
Seizures, tetany
⚠️ Causes
Vomiting, NG suction
Antacids, diuretics, ↓ K
📚 Metabolic Alkalosis — full study notes
The cheat sheet above is your quick recall card. These notes go deeper — what it is, what to do first, what must be reported, and what to teach.
Metabolic alkalosis is a high blood pH (above 7.45) caused by a loss of acid or a gain of bicarbonate, reflected in a high bicarbonate (HCO3 above 26). Common causes include prolonged vomiting or nasogastric suction (loss of stomach acid), excessive antacid use, and overuse of diuretics that waste potassium and hydrogen. The body compensates by slowing and shallowing breathing to retain CO2 and lower pH. Alkalosis increases neuromuscular excitability and is often paired with hypokalemia.
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Key points
Understand these first
ABG pattern: high pH (over 7.45) with high HCO3 (over 26 mEq/L); the bicarbonate change drives the disorder.
Increased neuromuscular excitability produces tingling of fingers and toes, muscle cramps, tremors, hyperactive reflexes, and tetany.
Hypokalemia commonly accompanies metabolic alkalosis and worsens dysrhythmia risk.
Neurologic signs include dizziness, confusion, irritability, and possible seizures.
Vomiting and gastric suctioning are the most common causes due to loss of hydrochloric acid.
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Nursing priorities
What to do, in order
Treat the cause: control vomiting, manage NG suction, and review diuretic and antacid use.
Replace fluids with isotonic saline and replace potassium as ordered.
Monitor ABGs, electrolytes (especially potassium and calcium), and cardiac rhythm.
Institute safety and seizure precautions for clients with tetany or altered mental status.
Monitor respiratory status, since compensatory hypoventilation can lower oxygenation.
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Red flags — report now
Escalate immediately
Tetany, seizures, or dysrhythmias - notify provider immediately.
Severe hypokalemia with ECG changes - report and treat urgently.
pH above 7.55 with neuromuscular instability - escalate.
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Labs & values
Numbers to know
pH normal 7.35-7.45; metabolic alkalosis pH greater than 7.45
HCO3 normal 22-26 mEq/L; increased (over 26) in metabolic alkalosis
PaCO2 normal 35-45 mmHg; increased with respiratory compensation; check potassium
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Patient teaching
What patients must know
Do not overuse antacids or baking soda for stomach upset.
Use diuretics exactly as prescribed and keep follow-up labs.
Report persistent vomiting, muscle cramps, tingling, or palpitations.
❓ Metabolic Alkalosis: NCLEX FAQs
What are the priority nursing interventions for Metabolic Alkalosis?
Treat the cause: control vomiting, manage NG suction, and review diuretic and antacid use. Replace fluids with isotonic saline and replace potassium as ordered. Monitor ABGs, electrolytes (especially potassium and calcium), and cardiac rhythm. Institute safety and seizure precautions for clients with tetany or altered mental status.
What are the warning signs of Metabolic Alkalosis a nurse must report?
Tetany, seizures, or dysrhythmias - notify provider immediately. Severe hypokalemia with ECG changes - report and treat urgently. pH above 7.55 with neuromuscular instability - escalate.
What do I need to know about Metabolic Alkalosis for the NCLEX?
ABG pattern: high pH (over 7.45) with high HCO3 (over 26 mEq/L); the bicarbonate change drives the disorder. Respiratory compensation causes slow, shallow breathing to retain CO2, raising PaCO2. Increased neuromuscular excitability produces tingling of fingers and toes, muscle cramps, tremors, hyperactive reflexes, and tetany. Hypokalemia commonly accompanies metabolic alkalosis and worsens dysrhythmia risk.
What patient teaching is important for Metabolic Alkalosis?
Do not overuse antacids or baking soda for stomach upset. Use diuretics exactly as prescribed and keep follow-up labs. Report persistent vomiting, muscle cramps, tingling, or palpitations.
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Quick Tip
ABG pattern: high pH (over 7.45) with high HCO3 (over 26 mEq/L); the bicarbonate change drives the disorder.