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Metabolic Alkalosis — NCLEX Cheat Sheet

↑ pH, ↑ HCO₃⁻
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👤 By the CinnaRN Clinical Content Team 🕐 Updated 2026-08-23 🏷️ Physiological Adaptation 🔖 Free to read, print, and share

Also known as: alkalosis · high pH · high bicarb · alkaline blood

Metabolic Alkalosis — medical illustration
Metabolic Alkalosis — medical illustration. Illustration: OpenStax via Wikimedia Commons, CC BY 3.0.
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Use this quick-reference guide to spot, treat, and prevent Metabolic Alkalosis on the NCLEX. Keep it handy during review and on exam day!

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📒 The 1-minute cheat sheet

🧪 Labs

  • pH > 7.45, HCO₃ > 26
  • Lungs retain CO₂ (slow/shallow)

🩺 Signs

  • ↓ K → cramps, weakness
  • Tetany, tingling, tremor
  • Dizzy, confusion, ↑ DTRs

🚩 Report

  • Dysrhythmias from ↓ K
  • Seizures, tetany

⚠️ Causes

  • Vomiting, NG suction
  • Antacids, diuretics, ↓ K

📚 Metabolic Alkalosis — full study notes

The cheat sheet above is your quick recall card. These notes go deeper — what it is, what to do first, what must be reported, and what to teach.

Metabolic alkalosis is a high blood pH (above 7.45) caused by a loss of acid or a gain of bicarbonate, reflected in a high bicarbonate (HCO3 above 26). Common causes include prolonged vomiting or nasogastric suction (loss of stomach acid), excessive antacid use, and overuse of diuretics that waste potassium and hydrogen. The body compensates by slowing and shallowing breathing to retain CO2 and lower pH. Alkalosis increases neuromuscular excitability and is often paired with hypokalemia.
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Key points

Understand these first

Nursing priorities

What to do, in order
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Red flags — report now

Escalate immediately
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Labs & values

Numbers to know
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Patient teaching

What patients must know

❓ Metabolic Alkalosis: NCLEX FAQs

What are the priority nursing interventions for Metabolic Alkalosis?

Treat the cause: control vomiting, manage NG suction, and review diuretic and antacid use. Replace fluids with isotonic saline and replace potassium as ordered. Monitor ABGs, electrolytes (especially potassium and calcium), and cardiac rhythm. Institute safety and seizure precautions for clients with tetany or altered mental status.

What are the warning signs of Metabolic Alkalosis a nurse must report?

Tetany, seizures, or dysrhythmias - notify provider immediately. Severe hypokalemia with ECG changes - report and treat urgently. pH above 7.55 with neuromuscular instability - escalate.

What do I need to know about Metabolic Alkalosis for the NCLEX?

ABG pattern: high pH (over 7.45) with high HCO3 (over 26 mEq/L); the bicarbonate change drives the disorder. Respiratory compensation causes slow, shallow breathing to retain CO2, raising PaCO2. Increased neuromuscular excitability produces tingling of fingers and toes, muscle cramps, tremors, hyperactive reflexes, and tetany. Hypokalemia commonly accompanies metabolic alkalosis and worsens dysrhythmia risk.

What patient teaching is important for Metabolic Alkalosis?

Do not overuse antacids or baking soda for stomach upset. Use diuretics exactly as prescribed and keep follow-up labs. Report persistent vomiting, muscle cramps, tingling, or palpitations.

Quick Tip

ABG pattern: high pH (over 7.45) with high HCO3 (over 26 mEq/L); the bicarbonate change drives the disorder.

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