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Physiological Adaptation↓ dopamine → TRAP

Parkinson DiseaseNCLEX cheat sheet

Parkinson disease is a progressive degenerative disorder caused by loss of dopamine-producing neurons in the brain's basal ganglia, leading to impaired movement control.

19 key facts 5 practice questions Reviewed Oct 2026
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Mechanism

  • ↓ dopamine in basal ganglia
  • Progressive, no cure

Signs

  • Tremor: pill-rolling at rest
  • Rigidity, akinesia, postural instab.
  • Shuffling gait, mask face, drool

Meds

  • Levodopa-carbidopa = mainstay
  • Avoid protein/B6 with levodopa
  • No MAOIs → HTN crisis

Do

  • Fall precautions, PT, exercise
  • Small frequent meals, thicken liquids
Red flag to remember

Difficulty swallowing with choking or coughing on food signals aspiration risk, report and reassess the diet.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A nurse assesses a client newly diagnosed with Parkinson disease. Which classic finding does the nurse expect to observe?

What is parkinson disease?

The dopamine deficiency produces the classic triad of tremor, rigidity, and bradykinesia. It mainly affects older adults and worsens over time. Remember TRAP: Tremor, Rigidity, Akinesia/bradykinesia, Postural instability.

Parkinson Disease illustrated

Parkinson disease: loss of dopamine-producing neurons
Parkinson disease: loss of dopamine-producing neurons. Illustration: BruceBlaus via Wikimedia Commons, CC BY 3.0.

Key points to remember

  • A resting 'pill-rolling' tremor that decreases with purposeful movement is the hallmark sign.
  • Cogwheel rigidity, bradykinesia (slow movement), and a stooped, shuffling, festinating gait are characteristic.
  • A masklike facial expression, soft monotone speech, drooling, and small handwriting (micrographia) are common.
  • Postural instability increases the risk of falls as the disease progresses.
  • Levodopa-carbidopa is the cornerstone drug; it replenishes dopamine and improves motor symptoms.

Signs & symptoms

  • Tremor: pill-rolling at rest
  • Rigidity, akinesia, postural instab.
  • Shuffling gait, mask face, drool

Nursing priorities

  1. Implement fall precautions and promote a safe environment, since postural instability and shuffling gait raise fall risk.
  2. Administer antiparkinsonian medications on time to maintain consistent motor control.
  3. Provide small, frequent, high-calorie soft meals and allow extra time to eat to prevent aspiration and weight loss.
  4. Encourage active and passive range of motion, daily exercise, and ambulation to maintain mobility.
  5. Teach techniques to initiate movement, such as rocking and consciously lifting the feet, to overcome freezing.

Patient teaching

  • Take levodopa-carbidopa exactly as scheduled; effects may take weeks, and avoid high-protein meals at dose time as protein can reduce absorption.
  • Change positions slowly to prevent dizziness from orthostatic hypotension, and that urine/sweat may darken on levodopa.
  • Use assistive devices, perform daily exercise and stretching, and prevent constipation with fluids and fiber.

Red flags: report now

  • Difficulty swallowing with choking or coughing on food signals aspiration risk, report and reassess the diet.
  • Sudden severe rigidity, high fever, and altered mentation may indicate neuroleptic malignant-like syndrome from abrupt medication withdrawal.
  • Significant orthostatic hypotension from medications increases fall and injury risk.

References

Clinical references for this topic

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