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Physiological Adaptation↓ arterial flow to limbs

Peripheral Arterial DiseaseNCLEX cheat sheet

Peripheral arterial disease is narrowing of the arteries in the limbs, usually from atherosclerosis, that reduces blood flow to the extremities.

23 key facts 5 practice questions Reviewed Oct 2026
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Signs

  • Intermittent claudication
  • Cool, pale, hairless, shiny skin
  • ↓ pulses, pain worse w/ elevation
  • Pain relieved by dangling

Do

  • Dangle legs, keep warm
  • Walk to tolerance, foot care

Avoid

  • No leg elevation
  • No smoking, no crossing legs
  • No tight clothing/cold

Report

  • Critical ischemia → gangrene
Key takeaway

Intermittent claudication is cramping leg pain with walking that is relieved by rest.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A client with peripheral arterial disease (PAD) reports leg pain that occurs with walking and is relieved by rest. The nurse documents this classic finding as which term?

What is peripheral arterial disease?

The reduced arterial supply causes pain with activity (intermittent claudication), cool pale limbs, and poor wound healing. The key contrast for the exam is arterial versus venous insufficiency: arterial problems mean tissue is not getting enough oxygenated blood.

Peripheral Arterial Disease illustrated

Peripheral Arterial Disease — medical illustration
Peripheral Arterial Disease — medical illustration. Illustration: BruceBlaus via Wikimedia Commons, CC BY 3.0.

Key points to remember

  • Intermittent claudication is cramping leg pain with walking that is relieved by rest.
  • Affected limbs are cool, pale, shiny, and hairless with diminished or absent pulses and thick toenails.
  • Pain worsens with elevation and improves with dependent (dangling) positioning because gravity aids arterial flow.
  • Arterial ulcers are painful, round, and on the toes or pressure points with little drainage.
  • Major risk factors are smoking, diabetes, hypertension, and high cholesterol.

Signs & symptoms

  • Intermittent claudication
  • Cool, pale, hairless, shiny skin
  • ↓ pulses, pain worse w/ elevation
  • Pain relieved by dangling

Nursing priorities

  1. Assess and document peripheral pulses, skin color, temperature, capillary refill, and pain.
  2. Position the legs in a dependent or neutral position rather than elevated to promote arterial flow.
  3. Encourage a gradual walking program to promote collateral circulation as tolerated.
  4. Promote smoking cessation and protect the extremities from injury and temperature extremes.
  5. Administer antiplatelet medications and manage diabetes, hypertension, and cholesterol as ordered.

Labs & values

Ankle-brachial index (ABI): normal 0.9-1.3; below0.9 indicates PAD
Lipid panel: LDL goal less than100 mg/dL
Hemoglobin A1c to assess diabetes control

Patient teaching

  • Stop smoking completely, as nicotine constricts arteries and worsens the disease.
  • Inspect the feet daily, wear well-fitting shoes, avoid going barefoot, and protect the legs from heat, cold, and injury.
  • Walk regularly to the point of pain then rest, keep the legs in a dependent position, and avoid crossing the legs or tight clothing.

Red flags: report now

  • Sudden severe leg pain with pallor, pulselessness, coldness, and numbness signals acute arterial occlusion and is a limb-threatening emergency.
  • A new non-healing ulcer or signs of gangrene must be reported immediately.
  • Loss of a previously present pulse requires immediate provider notification.

References

Clinical references for this topic

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