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Physiological AdaptationPink frothy sputum = hallmark

Pulmonary EdemaNCLEX cheat sheet

Pulmonary edema is the accumulation of fluid in the alveoli and lung interstitium that severely impairs gas exchange, most commonly from left-sided heart failure that backs blood up into the lungs (cardiogenic).

25 key facts 4 practice questions Reviewed Oct 2026
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Causes

  • Left-sided HF #1 cause
  • Fluid overload, MI, valve disease

Signs

  • Pink frothy sputum = classic
  • Crackles, dyspnea, orthopnea
  • Anxiety, restless, ↓ SpO2

Do

  • High Fowler's, legs dependent
  • O2, morphine, furosemide IV
  • Nitro → ↓ preload; monitor I&O

Avoid

  • Lying flat → worsens dyspnea
  • IV fluids unless ordered
Key takeaway

Severe dyspnea, orthopnea, and pink frothy sputum are the classic signs.

Before you read

Test yourself first: 4 questions

Question 1 of 4

A nurse auscultates the posterior chest of an adult and hears high-pitched, discontinuous popping sounds at the lung bases that do not clear with coughing. How should the nurse document this finding?

What is pulmonary edema?

It is an acute life-threatening emergency. The hallmark is pink, frothy sputum with severe dyspnea and a sense of suffocation.

Pulmonary Edema illustrated

Pulmonary Edema — medical illustration
Pulmonary Edema — medical illustration. Illustration: Servier Medical Art via Wikimedia Commons, CC BY-SA 3.0.

Key points to remember

  • Severe dyspnea, orthopnea, and pink frothy sputum are the classic signs.
  • Coarse crackles heard throughout the lung fields and tachypnea reflect alveolar flooding.
  • Anxiety, restlessness, a feeling of suffocation, and tachycardia are common.
  • Cool clammy skin, cyanosis, and hypoxemia develop as gas exchange fails.
  • The patient often sits bolt upright and gasping, and may have an S3 heart sound with cardiogenic causes.
  • It progresses rapidly and can lead to respiratory failure without prompt treatment.

Common causes

  • Left-sided HF #1 cause
  • Fluid overload, MI, valve disease

Signs & symptoms

  • Pink frothy sputum = classic
  • Crackles, dyspnea, orthopnea
  • Anxiety, restless, ↓ SpO2

Nursing priorities

  1. Place the patient in high Fowler's with legs dependent to decrease venous return (preload).
  2. Administer high-flow oxygen and prepare for noninvasive ventilation or intubation.
  3. Give IV loop diuretics (furosemide) to reduce fluid volume as ordered.
  4. Administer vasodilators (nitroglycerin) and morphine as ordered to reduce preload and anxiety.
  5. Monitor oxygen saturation, vital signs, urine output, and lung sounds continuously.

Labs & values

BNP elevated (normal <100 pg/mL) in cardiogenic pulmonary edema
ABG: hypoxemia (PaO2 <80), early respiratory alkalosis then acidosis as it worsens
Monitor SpO2 (normal95-100%)

Patient teaching

  • Weigh daily at the same time and report a gain of 2 to 3 pounds in a day or 5 pounds in a week.
  • Follow a low-sodium diet and any prescribed fluid restriction.
  • Take diuretics and heart medications as prescribed and report increasing shortness of breath or swelling.

Red flags: report now

  • Pink frothy sputum with severe respiratory distress is an emergency requiring immediate intervention.
  • Falling oxygen saturation, decreasing level of consciousness, or hypotension signal decompensation.
  • Worsening crackles and rising respiratory rate despite treatment require rapid escalation.

References

Clinical references for this topic

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