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Physiological AdaptationClot blocks lung artery

Pulmonary EmbolismNCLEX cheat sheet

A pulmonary embolism is an obstruction of the pulmonary artery or a branch, most often by a deep vein thrombosis that traveled from the legs, blocking blood flow to lung tissue.

24 key facts 5 practice questions Reviewed Oct 2026
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Signs

  • Sudden SOB, sharp chest pain
  • Tachycardia, tachypnea, ↓ O₂
  • Anxiety, hemoptysis, cough

Do

  • O₂ high-flow, semi-Fowler's
  • Anticoag heparin, thrombolytics
  • IV access, monitor, stay calm

Report

  • Sudden death, ↓ BP, shock

Teach

  • Prevent: ambulate, SCDs, AC
  • Risk: DVT, surgery, immobility
Red flag to remember

Sudden severe dyspnea, hypotension, or loss of consciousness signals a massive PE, call for emergency help.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A client with a massive pulmonary embolism is in obstructive shock. Which assessment finding would the nurse most expect?

What is pulmonary embolism?

It is a life-threatening emergency because it impairs gas exchange and can cause sudden cardiovascular collapse. Risk factors follow Virchow's triad: venous stasis, hypercoagulability, and endothelial injury (immobility, surgery, pregnancy, oral contraceptives).

Pulmonary Embolism illustrated

Pulmonary embolism: a clot lodged in a pulmonary artery
Pulmonary embolism: a clot lodged in a pulmonary artery. Illustration: https://www.scientificanimations.com via Wikimedia Commons, CC BY-SA 4.0.

Key points to remember

  • Sudden onset of dyspnea and sharp pleuritic chest pain are the most common presenting signs.
  • Tachypnea, tachycardia, anxiety, and a sense of impending doom are frequent.
  • Hypoxemia, cough, and sometimes hemoptysis occur as lung tissue is deprived of perfusion.
  • A large saddle embolus can cause hypotension, jugular vein distention, and obstructive shock.
  • ABGs often show respiratory alkalosis with hypoxemia and a low PaCO2 from hyperventilation.
  • Spiral CT pulmonary angiography is the gold-standard diagnostic test; a positive D-dimer is sensitive but not specific.

Signs & symptoms

  • Sudden SOB, sharp chest pain
  • Tachycardia, tachypnea, ↓ O₂
  • Anxiety, hemoptysis, cough

Nursing priorities

  1. Apply high-flow oxygen and place the patient in high Fowler's position immediately.
  2. Notify the rapid response or provider and prepare for anticoagulation.
  3. Administer anticoagulants (heparin) as ordered, and thrombolytics for massive PE with hemodynamic instability.
  4. Establish IV access and continuously monitor cardiac rhythm, oxygenation, and vital signs.
  5. Keep the patient calm and on bed rest to reduce oxygen demand and clot dislodgement.

Labs & values

D-dimer elevated (normal <0.5 mcg/mL); sensitive but not specific
ABG: hypoxemia (PaO2 <80) and respiratory alkalosis (low PaCO2)
Monitor aPTT for heparin (therapeutic1.5-2.5x control)

Patient teaching

  • Prevent clots by ambulating early after surgery, doing leg exercises, and staying hydrated.
  • Avoid prolonged immobility, take stretch breaks on long trips, and use prescribed compression devices.
  • While on anticoagulants, report any unusual bleeding or bruising and attend lab monitoring.

Red flags: report now

  • Sudden severe dyspnea, hypotension, or loss of consciousness signals a massive PE, call for emergency help.
  • Falling blood pressure with rising heart rate indicates obstructive shock and impending arrest.
  • Signs of bleeding during anticoagulant or thrombolytic therapy require immediate evaluation.
  • Never massage the legs of a patient with suspected DVT, which can dislodge the clot.

References

Clinical references for this topic

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