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Safety & Infection ControlCross placenta → fetal harm

TORCH InfectionsNCLEX cheat sheet

TORCH is a group of maternal infections that cross the placenta or are acquired at birth and cause congenital anomalies, miscarriage, or neonatal illness.

21 key facts 3 practice questions Reviewed Oct 2026
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Def

  • Toxo, Other, Rubella, CMV, Herpes
  • Other = syphilis, HIV, parvo, varicella

Signs

  • IUGR, microcephaly, hearing loss
  • Rash, cataracts, hepatosplenomegaly

Teach

  • Toxo → avoid cat litter, raw meat
  • Rubella → MMR before pregnancy, not during
  • MMR is live → no in pregnancy

Do

  • Herpes lesions → C-section delivery
  • Screen prenatally, treat early
Red flag to remember

Never give live virus vaccines (MMR, varicella) during pregnancy; advise avoiding pregnancy for 4 weeks after.

Before you read

Test yourself first: 3 questions

Question 1 of 3

A nurse is teaching a nursing student about the most important measure to prevent the spread of health-care-associated infections. Which statement by the student indicates correct understanding?

What is torch infections?

The acronym stands for Toxoplasmosis, Other (syphilis, varicella, parvovirus B19, hepatitis, HIV, Zika), Rubella, Cytomegalovirus (CMV), and Herpes simplex virus. Prevention and early maternal screening are key because many infections are asymptomatic in the mother but devastating to the fetus.

Key points to remember

  • Toxoplasmosis is acquired from cat litter and raw/undercooked meat and can cause hydrocephalus, chorioretinitis, and intracranial calcifications.
  • Rubella (first-trimester) causes cataracts, deafness, and cardiac defects; the MMR vaccine is contraindicated during pregnancy because it is a live vaccine.
  • Cytomegalovirus is the most common congenital viral infection and a leading cause of congenital hearing loss.
  • Active genital herpes lesions at delivery require cesarean birth to prevent neonatal HSV.
  • Many TORCH infections are subclinical in the mother but cause IUGR, microcephaly, rash, jaundice, or hearing/vision loss in the neonate.
  • Untreated maternal syphilis can cause stillbirth and congenital syphilis; it is treated with penicillin.

Signs & symptoms

  • IUGR, microcephaly, hearing loss
  • Rash, cataracts, hepatosplenomegaly

Nursing priorities

  1. Reinforce prevention: avoid cat litter and undercooked meat, practice hand hygiene, and screen for immunity.
  2. Administer rubella vaccine postpartum (not during pregnancy) to nonimmune mothers.
  3. Identify active herpes lesions at admission and notify the provider for possible cesarean delivery.
  4. Implement appropriate isolation and standard precautions for infected neonates and report cases as required.
  5. Ensure pregnant clients avoid live vaccines during pregnancy.

Labs & values

Maternal TORCH titers/serology (IgM positive suggests acute infection; IgG indicates immunity/past exposure)
Nontreponemal syphilis screen (RPR/VDRL) confirmed by treponemal test

Patient teaching

  • Pregnant women should not change cat litter and should cook meat thoroughly.
  • Wash hands frequently, especially around young children, to reduce CMV exposure.
  • Get rubella immunity checked before or early in pregnancy and vaccinate after delivery if nonimmune.

Red flags: report now

  • Never give live virus vaccines (MMR, varicella) during pregnancy; advise avoiding pregnancy for 4 weeks after.
  • Active genital herpes lesions in labor: never proceed with vaginal birth; report for cesarean.
  • Report neonatal signs of congenital infection (microcephaly, rash, jaundice, seizures, poor feeding).

References

Clinical references for this topic

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