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Physiological AdaptationDysuria, frequency, urgency

Urinary Tract InfectionNCLEX cheat sheet

A urinary tract infection is a bacterial infection of the urinary system, most often the bladder (cystitis), usually caused by E. coli ascending from the perineum.

26 key facts 5 practice questions Reviewed Oct 2026
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Causes

  • E. coli #1, ascending bacteria
  • F > M, catheters, retention

Signs

  • dysuria, frequency, urgency
  • cloudy/foul urine, suprapubic pain
  • elderly: confusion = key sign

Labs

  • ↑WBC, +nitrites, +leukocyte est
  • culture BEFORE antibiotics

Teach

  • ↑fluids 2-3 L/day, finish abx
  • wipe front→back, void after sex
  • cotton underwear, no bubble baths
Red flag to remember

Flank pain, high fever, and chills - infection may have reached the kidneys (pyelonephritis); report.

Before you read

Test yourself first: 5 questions

Question 1 of 5

An 82-year-old presents with new-onset confusion, low-grade fever, and urinary frequency. Which underlying cause should the nurse suspect first?

What is urinary tract infection?

Women are at higher risk due to a shorter urethra. It matters because untreated lower-tract infection can ascend to the kidneys (pyelonephritis) or cause urosepsis, especially in older adults.

Urinary Tract Infection illustrated

Urinary tract infection of the bladder and urethra
Urinary tract infection of the bladder and urethra. Illustration: https://www.myupchar.com/en via Wikimedia Commons, CC BY-SA 4.0.

Key points to remember

  • Classic symptoms are dysuria (burning), urinary frequency, urgency, and suprapubic pain or pressure.
  • Urine may be cloudy, dark, foul-smelling, or contain blood (hematuria).
  • In older adults, new-onset confusion or behavior change is often the FIRST and only sign.
  • E. coli from the GI tract is the most common causative organism.
  • Indwelling catheters are a leading cause of healthcare-associated UTIs.
  • Positive nitrites and leukocyte esterase on urinalysis suggest bacterial infection.

Common causes

  • E. coli #1, ascending bacteria
  • F > M, catheters, retention

Signs & symptoms

  • dysuria, frequency, urgency
  • cloudy/foul urine, suprapubic pain
  • elderly: confusion = key sign

Nursing priorities

  1. Obtain a clean-catch or catheter urine specimen for culture BEFORE starting antibiotics.
  2. Administer prescribed antibiotics and encourage increased fluid intake (2-3 L/day unless contraindicated).
  3. Provide analgesics such as phenazopyridine for dysuria and assess pain.
  4. Promote perineal hygiene and remove unnecessary indwelling catheters early.
  5. Monitor for signs the infection is ascending (flank pain, fever).

Labs & values

Urinalysis: positive nitrites, leukocyte esterase, WBCs, bacteria
Urine culture: greater than100,000 colonies confirms infection
WBC: normal5,000-10,000/mm3 (may be elevated)

Patient teaching

  • Wipe front to back, void after intercourse, and avoid bubble baths and irritants.
  • Drink plenty of fluids and finish the entire antibiotic course even if symptoms improve.
  • Phenazopyridine turns urine reddish-orange and may stain clothing; this is harmless.

Red flags: report now

  • Flank pain, high fever, and chills - infection may have reached the kidneys (pyelonephritis); report.
  • New confusion in an older adult - report and evaluate for UTI/urosepsis.
  • Signs of urosepsis (hypotension, tachycardia, fever) - emergency escalation.
  • Do not delay obtaining the culture before antibiotics when ordered.

References

Clinical references for this topic

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