👤 By the CinnaRN Clinical Content Team🕐 Updated 2026-08-23🏷️ Physiological Adaptation🔖 Free to read, print, and share
Also known as: breast carcinoma · mammary cancer
Breast cancer within the breast tissue. Illustration: BruceBlaus via Wikimedia Commons, CC BY-SA 4.0.
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Use this quick-reference guide to spot, treat, and prevent Breast Cancer on the NCLEX. Keep it handy during review and on exam day!
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📒 The 1-minute cheat sheet
🩺 Signs
Hard fixed painless lump, upper-outer
Skin dimpling, peau d'orange, nipple retraction
Bloody/clear unilateral nipple discharge
📌 Risk
BRCA1/2, family hx, female, age ↑
Early menarche, late menopause, nulliparity
📌 Dx
Mammogram, US, biopsy = definitive
Receptors: ER/PR/HER2 → guide tx
✅ Do
Post-mastectomy: arm elevated, no BP/IV
Watch lymphedema → no constriction
Tamoxifen → ↑ clot/DVT risk
📚 Breast Cancer — full study notes
The cheat sheet above is your quick recall card. These notes go deeper — what it is, what to do first, what must be reported, and what to teach.
Breast cancer is a malignant tumor of breast tissue and is the most common cancer in women. The classic presentation is a painless, hard, fixed, irregular lump, most often in the upper outer quadrant. Risk rises with age, family history, BRCA1/BRCA2 mutations, prolonged estrogen exposure, and obesity. Early detection through screening and self-awareness improves survival.
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Key points
Understand these first
The classic sign is a single, hard, painless, fixed, irregular lump, frequently in the upper outer quadrant.
Other signs include nipple retraction, skin dimpling, peau d'orange (orange-peel skin), and bloody or clear nipple discharge.
Risk factors include female sex, increasing age, BRCA1/BRCA2 mutations, family history, early menarche/late menopause, nulliparity, and prolonged estrogen exposure.
Hormone receptor (ER/PR) and HER2 status guide therapy; ER-positive tumors respond to tamoxifen or aromatase inhibitors.
Treatment may include lumpectomy or mastectomy, sentinel lymph node biopsy, radiation, chemotherapy, and targeted/hormonal therapy.
After axillary lymph node dissection, the affected arm is at risk for lymphedema.
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Nursing priorities
What to do, in order
After mastectomy, position the affected arm elevated on a pillow to promote lymph drainage.
Protect the affected arm: no BP measurements, venipunctures, or injections on that side.
Encourage progressive arm exercises as ordered to restore range of motion and prevent contractures.
Provide emotional support and address body image and sexuality concerns.
Monitor the surgical site and drains for bleeding, infection, and excessive output.
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Red flags — report now
Escalate immediately
Signs of lymphedema or infection in the affected arm (swelling, redness, warmth) require prompt reporting.
Never take blood pressure, draw blood, or give injections in the arm on the operative/lymph node dissection side.
Sudden severe arm swelling, chest pain, or shortness of breath needs immediate evaluation.
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Labs & values
Numbers to know
Tumor markers CA 15-3 / CA 27-29: may be elevated (used for monitoring, not screening)
ER/PR receptor status: positive or negative
HER2 status: positive or negative
BRCA1/BRCA2 genetic testing: as indicated
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Patient teaching
What patients must know
Protect the affected arm: avoid blood draws, BP, injections, heavy lifting, tight clothing/jewelry, and cuts on that side.
Perform prescribed arm exercises and report any swelling, redness, or signs of lymphedema or infection.
Follow recommended screening: mammography and clinical exams per guidelines; report any new lump or change.
Practice monthly breast self-awareness and know normal versus abnormal findings.
For hormonal therapy like tamoxifen, report leg pain/swelling or abnormal vaginal bleeding (clot and endometrial cancer risk).
❓ Breast Cancer: NCLEX FAQs
What are the priority nursing interventions for Breast Cancer?
After mastectomy, position the affected arm elevated on a pillow to promote lymph drainage. Protect the affected arm: no BP measurements, venipunctures, or injections on that side. Encourage progressive arm exercises as ordered to restore range of motion and prevent contractures. Provide emotional support and address body image and sexuality concerns.
What are the warning signs of Breast Cancer a nurse must report?
Signs of lymphedema or infection in the affected arm (swelling, redness, warmth) require prompt reporting. Never take blood pressure, draw blood, or give injections in the arm on the operative/lymph node dissection side. Sudden severe arm swelling, chest pain, or shortness of breath needs immediate evaluation.
What do I need to know about Breast Cancer for the NCLEX?
The classic sign is a single, hard, painless, fixed, irregular lump, frequently in the upper outer quadrant. Other signs include nipple retraction, skin dimpling, peau d'orange (orange-peel skin), and bloody or clear nipple discharge. Risk factors include female sex, increasing age, BRCA1/BRCA2 mutations, family history, early menarche/late menopause, nulliparity, and prolonged estrogen exposure. Hormone receptor (ER/PR) and HER2 status guide therapy; ER-positive tumors respond to tamoxifen or aromatase inhibitors.
What patient teaching is important for Breast Cancer?
Protect the affected arm: avoid blood draws, BP, injections, heavy lifting, tight clothing/jewelry, and cuts on that side. Perform prescribed arm exercises and report any swelling, redness, or signs of lymphedema or infection. Follow recommended screening: mammography and clinical exams per guidelines; report any new lump or change. Practice monthly breast self-awareness and know normal versus abnormal findings.
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Quick Tip
The classic sign is a single, hard, painless, fixed, irregular lump, frequently in the upper outer quadrant.