👤 By the CinnaRN Clinical Content Team🕐 Updated 2026-08-23🏷️ Physiological Adaptation🔖 Free to read, print, and share
Also known as: gallbladder inflammation · gallbladder attack · inflamed gallbladder · gallstones · gall bladder pain
Gallstones in the gallbladder and bile duct. Illustration: BruceBlaus via Wikimedia Commons, CC BY-SA 4.0.
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Use this quick-reference guide to spot, treat, and prevent Cholecystitis on the NCLEX. Keep it handy during review and on exam day!
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📒 The 1-minute cheat sheet
⚠️ Causes
Gallstones block cystic duct
Fat, female, forty, fertile
🩺 Signs
RUQ pain → right shoulder
Murphy's sign +, worse w/ fatty
N/V, fever, clay stool, jaundice
✅ Do
NPO, IV fluids, pain meds
Lap cholecystectomy = definitive
Low-fat diet, small meals
🚩 Report
T-tube >500 mL/day or no drainage
Fever, ↑ pain = perforation
📚 Cholecystitis — full study notes
The cheat sheet above is your quick recall card. These notes go deeper — what it is, what to do first, what must be reported, and what to teach.
Cholecystitis is inflammation of the gallbladder, most often caused by a gallstone (cholelithiasis) obstructing the cystic duct and blocking bile flow. Risk factors are summarized by the 4 F's: Female, Forty, Fat, and Fertile. Pain typically follows a fatty meal because fat triggers gallbladder contraction. Bile obstruction can back up and cause jaundice and clay-colored stools.
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Key points
Understand these first
Right upper quadrant pain that may radiate to the right shoulder or scapula, often after a high-fat meal.
Murphy sign is positive: pain and inspiratory arrest when the RUQ is palpated during deep breath.
Nausea, vomiting, fever, and indigestion (dyspepsia) are common.
Obstruction of bile flow causes jaundice, dark amber urine, clay-colored stools, and pruritus.
Bile is needed to absorb fat-soluble vitamins, so deficiency of A, D, E, and K may occur.
The classic risk profile is the 4 F's: female, forty, fat (obese), and fertile.
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Nursing priorities
What to do, in order
Keep the patient NPO during acute attacks to rest the gallbladder.
Administer prescribed analgesics and antiemetics; provide IV fluids as ordered.
Prepare and educate the patient for cholecystectomy, often laparoscopic.
Monitor for signs of bile duct obstruction such as worsening jaundice and pale stools.
Administer fat-soluble vitamin supplements and vitamin K if bile flow is impaired, as ordered.
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Red flags — report now
Escalate immediately
Fever, severe RUQ pain, and jaundice may indicate ascending cholangitis or sepsis requiring urgent care.
Signs of gallbladder rupture or peritonitis (rigid abdomen, rebound tenderness) need immediate escalation.
Clay-colored stools with dark urine and worsening jaundice signal complete bile obstruction.
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Labs & values
Numbers to know
WBC: 5,000-10,000/mm3 (elevated with inflammation/infection)
Total bilirubin: 0.3-1.0 mg/dL (elevated with obstruction)
Alkaline phosphatase and AST/ALT may be elevated
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Patient teaching
What patients must know
Eat a low-fat diet and avoid greasy, fried foods that trigger attacks.
After cholecystectomy, gradually reintroduce fats and report fever, increasing pain, or jaundice.
Report persistent RUQ pain, fever, or yellowing of the skin and eyes.
❓ Cholecystitis: NCLEX FAQs
What are the priority nursing interventions for Cholecystitis?
Keep the patient NPO during acute attacks to rest the gallbladder. Administer prescribed analgesics and antiemetics; provide IV fluids as ordered. Prepare and educate the patient for cholecystectomy, often laparoscopic. Monitor for signs of bile duct obstruction such as worsening jaundice and pale stools.
What are the warning signs of Cholecystitis a nurse must report?
Fever, severe RUQ pain, and jaundice may indicate ascending cholangitis or sepsis requiring urgent care. Signs of gallbladder rupture or peritonitis (rigid abdomen, rebound tenderness) need immediate escalation. Clay-colored stools with dark urine and worsening jaundice signal complete bile obstruction.
What do I need to know about Cholecystitis for the NCLEX?
Right upper quadrant pain that may radiate to the right shoulder or scapula, often after a high-fat meal. Murphy sign is positive: pain and inspiratory arrest when the RUQ is palpated during deep breath. Nausea, vomiting, fever, and indigestion (dyspepsia) are common. Obstruction of bile flow causes jaundice, dark amber urine, clay-colored stools, and pruritus.
What patient teaching is important for Cholecystitis?
Eat a low-fat diet and avoid greasy, fried foods that trigger attacks. After cholecystectomy, gradually reintroduce fats and report fever, increasing pain, or jaundice. Report persistent RUQ pain, fever, or yellowing of the skin and eyes.
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Quick Tip
Right upper quadrant pain that may radiate to the right shoulder or scapula, often after a high-fat meal.