CinnaRN Start free
Physiological AdaptationUnilateral throbbing + photophobia

Migraine HeadacheNCLEX cheat sheet

A migraine is a recurrent, throbbing, often unilateral headache caused by neurovascular changes, frequently accompanied by nausea, vomiting, and sensitivity to light (photophobia) and sound (phonophobia).

20 key facts 3 practice questions Reviewed Oct 2026
The 1-minute sheetCinnaRN

Signs

  • Unilateral throbbing/pulsating pain
  • Aura: flashing lights, zigzags
  • Photophobia + phonophobia + N/V

Triggers

  • Stress, hormones, missed meals
  • Tyramine: aged cheese, wine, MSG

Meds

  • Abortive: triptans (sumatriptan)
  • Prophylaxis: beta-blockers, topiramate
  • Triptans: hold if CAD/uncontrolled HTN

Do

  • Quiet, dark room, rest
  • Treat early → at aura onset
  • Cool cloth to forehead
Key takeaway

Pain is typically unilateral, pulsating/throbbing, and worsened by physical activity, lasting 4 to 72 hours.

Before you read

Test yourself first: 3 questions

Question 1 of 3

A client presents with the sudden onset of the worst headache of their life, neck stiffness, and photophobia. The nurse suspects which neurologic emergency?

What is migraine headache?

Some patients experience an aura (visual or sensory warning) before the headache begins. Attacks last 4 to 72 hours and are commonly triggered by stress, certain foods, hormonal changes, lack of sleep, and bright lights. Management focuses on aborting acute attacks and preventing recurrence.

Key points to remember

  • Pain is typically unilateral, pulsating/throbbing, and worsened by physical activity, lasting 4 to 72 hours.
  • Associated symptoms include nausea, vomiting, photophobia, and phonophobia; some patients have a preceding aura such as flashing lights or zigzag lines.
  • Abortive (acute) treatment: triptans (sumatriptan) and ergotamines cause vasoconstriction and are taken at onset; NSAIDs and antiemetics are adjuncts.
  • Triptans and ergotamines are contraindicated in coronary artery disease, uncontrolled hypertension, and pregnancy because of their vasoconstrictive effect.
  • Preventive drugs (beta-blockers like propranolol, topiramate, amitriptyline, CGRP antagonists) are used when attacks are frequent.

Signs & symptoms

  • Unilateral throbbing/pulsating pain
  • Aura: flashing lights, zigzags
  • Photophobia + phonophobia + N/V

Nursing priorities

  1. Provide a dark, quiet, cool environment and minimize light, noise, and movement during an attack.
  2. Administer abortive medication early at the first sign of a migraine for best effect.
  3. Apply cool cloth to the forehead and encourage rest in a comfortable position.
  4. Assess pain characteristics, triggers, and response to treatment, and help the patient keep a headache diary.
  5. Administer antiemetics as needed and monitor hydration if vomiting occurs.

Patient teaching

  • Identify and avoid personal triggers such as aged cheese, red wine, caffeine, MSG, stress, and skipped meals using a headache diary.
  • Take abortive medication at the very first sign of a migraine rather than waiting.
  • Rest in a dark, quiet room during attacks and maintain regular sleep, meals, and hydration.
  • Do not exceed prescribed triptan/ergotamine dosing to avoid medication-overuse (rebound) headaches.
  • Report headaches that change in pattern, become more severe, or are accompanied by new neurologic symptoms.

Red flags: report now

  • A sudden 'worst headache of my life,' headache with fever and stiff neck, or new focal deficits — these suggest hemorrhage, meningitis, or stroke, not a typical migraine.
  • Chest pain, tightness, or signs of coronary ischemia after taking a triptan or ergotamine — hold the drug and notify the provider.

References

Clinical references for this topic

CinnaRN website
CinnaRN app: a cheat sheet in the study feed
Study Migraine Headache in the app4,000+ NCLEX questions with a rationale on every answer, NGN case studies and timed mock exams.See how CinnaRN works
Start free
Want more Physiological Adaptation questions?We'll email you a free set on Migraine Headache. No account needed.

Was this helpful?

Free to start

Know migraine headache cold

4,000+ NCLEX questions with a rationale on every answer, NGN case studies and timed mock exams.

  • 4,000+ NCLEX questions with rationales
  • 51 NGN case studies
  • Timed CAT-style mock exams
  • 500+ cheat sheets
See how CinnaRN works
CinnaRN website
CinnaRN app: a cheat sheet in the study feed