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Physiological AdaptationCloudy effluent = peritonitis

Peritoneal DialysisNCLEX cheat sheet

Peritoneal dialysis uses the patient's own peritoneal membrane as the filter.

21 key facts 5 practice questions Reviewed Oct 2026
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Mech

  • dialysate into peritoneal cavity
  • fill → dwell → drain cycle
  • slower, done at home, daily

Do

  • STRICT sterile technique
  • warm dialysate before instilling
  • outflow > inflow expected

Report

  • CLOUDY effluent = peritonitis
  • fever, abd pain, rebound
  • outflow < inflow → check kink

Fix

  • slow drain → reposition, ambulate
  • watch hyperglycemia (glucose absorb)
Red flag to remember

Cloudy outflow, abdominal pain, fever, or rebound tenderness - signs of peritonitis; report immediately.

Before you read

Test yourself first: 5 questions

Question 1 of 5

The nurse is monitoring a client undergoing peritoneal dialysis. The outflow (drained) dialysate is cloudy. Which complication does this finding indicate?

What is peritoneal dialysis?

Dialysate is instilled into the abdominal cavity via a catheter, dwells while waste and fluid diffuse across the membrane, then is drained out. It can be done at home and offers more independence but carries a high risk of peritonitis. It is an alternative to hemodialysis for ESRD.

Key points to remember

  • The process is fill, dwell, and drain; the dwell time allows exchange of wastes and fluid.
  • Peritonitis is the most common and serious complication, signaled by CLOUDY drain effluent.
  • Drained dialysate (outflow) should be clear and pale yellow; cloudy fluid indicates infection.
  • Warming the dialysate before instillation promotes comfort and dilates peritoneal vessels for better exchange.
  • Outflow that is less than inflow (fluid retention) may indicate a kinked catheter, constipation, or fibrin clot.
  • Higher dextrose concentration dialysate pulls off more fluid but raises blood glucose.

Nursing priorities

  1. Use strict sterile technique with every exchange and catheter handling.
  2. Assess the color of outflow each exchange; report cloudy effluent as a sign of peritonitis.
  3. Track inflow versus outflow volumes and document; warm dialysate before instilling.
  4. Reposition the patient, check for kinks/constipation if outflow is inadequate.
  5. Monitor blood glucose because dialysate dextrose is absorbed.

Labs & values

Glucose: normal70-110 mg/dL (monitor for elevation from dialysate)
Potassium and BUN/Creatinine: monitor effectiveness
WBC of effluent: elevated with peritonitis
70110mg/dL Normal

Patient teaching

  • Always wash hands and use sterile technique; wear a mask during exchanges.
  • Report cloudy fluid, abdominal pain, or fever immediately as signs of infection.
  • Keep the catheter exit site clean and dry, prevent constipation, and weigh daily.

Red flags: report now

  • Cloudy outflow, abdominal pain, fever, or rebound tenderness - signs of peritonitis; report immediately.
  • Never instill cold dialysate or use breaks in sterile technique.
  • Significant fluid retention (much less drained than instilled) with respiratory difficulty - escalate.
  • Bloody or brown effluent (beyond the first few exchanges) - report.

References

Clinical references for this topic

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