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Seizure DisorderNCLEX cheat sheet

A seizure is a sudden, abnormal, excessive electrical discharge of neurons in the brain, and epilepsy is a chronic disorder of recurrent seizures.

19 key facts 5 practice questions Reviewed Oct 2026
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Types

  • Tonic-clonic = LOC + jerking
  • Absence = brief staring, no LOC
  • Aura may precede seizure

Do

  • Side-lying, protect head, time it
  • Loosen clothing, suction ready
  • Pad rails, stay with patient

Avoid

  • NEVER restrain or force airway
  • Nothing in mouth during seizure

Meds

  • Phenytoin, levetiracetam, valproate
  • Don't stop abruptly → status
  • Status epilepticus = give lorazepam
Key takeaway

A generalized tonic-clonic seizure has a tonic (stiffening) phase followed by a clonic (rhythmic jerking) phase.

Before you read

Test yourself first: 5 questions

Question 1 of 5

A client has been in a continuous generalized seizure for more than 5 minutes without regaining consciousness. The nurse recognizes this as status epilepticus and anticipates administering which medication FIRST?

What is seizure disorder?

Causes include head injury, infection, fever, tumors, metabolic imbalances, alcohol withdrawal, and missed antiepileptic medication. Nursing focus is protecting the airway and preventing injury during and after the event. Status epilepticus (continuous or back-to-back seizures) is a life-threatening emergency.

Key points to remember

  • A generalized tonic-clonic seizure has a tonic (stiffening) phase followed by a clonic (rhythmic jerking) phase.
  • An aura (strange smell, taste, or sensation) may warn of an impending seizure.
  • The postictal phase after a seizure features confusion, drowsiness, and sometimes temporary weakness.
  • Status epilepticus is continuous seizure activity lasting more than 5 minutes or repeated seizures without recovery between them.
  • Sudden withdrawal of antiepileptic drugs, alcohol withdrawal, and fever are common triggers.

Nursing priorities

  1. Protect the airway and turn the patient to the side to prevent aspiration during and after the seizure.
  2. Stay with the patient, ease them to the floor, and cushion/pad the head to prevent injury.
  3. Do NOT restrain the patient and do NOT put anything in the mouth.
  4. Time the seizure, note the type and progression, and loosen restrictive clothing.
  5. For status epilepticus, ensure airway/oxygen, IV access, and give IV lorazepam or diazepam as ordered.

Labs & values

Phenytoin therapeutic level (10-20 mcg/mL)
Sodium (normal135-145 mEq/L; hyponatremia can trigger seizures)
Blood glucose (normal70-110 mg/dL; hypoglycemia can trigger seizures)
1020mcg/mL Normal

Patient teaching

  • Take antiepileptic medication consistently and never stop it abruptly, as this can trigger status epilepticus.
  • Avoid driving until seizure-free per state law, and avoid swimming alone or working at heights.
  • Identify and avoid personal triggers such as alcohol, flashing lights, and sleep deprivation, and wear a medical alert bracelet.

Red flags: report now

  • Seizure lasting longer than 5 minutes or repeated seizures without regaining consciousness is status epilepticus, an emergency.
  • Cyanosis, absent respirations, or airway obstruction during a seizure requires immediate intervention.
  • Never insert a tongue blade or fingers into the mouth or attempt to restrain a seizing patient.

References

Clinical references for this topic

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